Basic information Safety Supplier Related

Mal-PEG4-Val-Cit-PAB-OH

Basic information Safety Supplier Related

Mal-PEG4-Val-Cit-PAB-OH Basic information

Product Name:
Mal-PEG4-Val-Cit-PAB-OH
Synonyms:
  • Mal-PEG4-Val-Cit-PAB-OH
  • L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
CAS:
2055041-39-7
MF:
C33H50N6O11
MW:
706.78
Product Categories:
  • PROTAC LINKER
  • ADC LINKER
Mol File:
2055041-39-7.mol
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Mal-PEG4-Val-Cit-PAB-OH Chemical Properties

Boiling point:
973.9±65.0 °C(Predicted)
Density 
1.269±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
pka
13.41±0.70(Predicted)
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Mal-PEG4-Val-Cit-PAB-OH Usage And Synthesis

Description

Mal-PEG4-Val-Cit-PAB-OH is a cleavable peptide linker. The Val-Cit was designed to be cleaved by Cathepsin B. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. PEG4 arm increases the aqueous solubility of the compound.

Mal-PEG4-Val-Cit-PAB-OHSupplier

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