Mal-PEG4-amine TFA salt
Mal-PEG4-amine TFA salt Basic information
- Product Name:
- Mal-PEG4-amine TFA salt
- Synonyms:
-
- Mal-PEG4-C2-NH2 TFA
- Mal-PEG5-amine
- 1-(14-amino-3,6,9,12-tetraoxatetradecyl)pyrrolidine-2,5-dione 2,2,2-trifluoroacetate
- CAS:
- 2512227-13-1
- MF:
- C16H25F3N2O8
- MW:
- 430.38
- Mol File:
- 2512227-13-1.mol
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Mal-PEG4-amine TFA salt Usage And Synthesis
Biological Activity
Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mal-PEG4-amine TFA saltSupplier
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Mal-PEG4-amine TFA salt(2512227-13-1)Related Product Information
- Mal-PEG5-COOtBu
- Mal-PEG6-NHS ester
- Mal-PEG2-alcohol
- Mal-PEG1-acid
- Mal-PEG2-t-butyl ester
- Mal-PEG1-t-butyl ester
- Mal-PEG6-amine TFA salt
- Mal-PEG4-propargyl
- Mal-PEG5-acid
- Mal-PEG3-NHS ester
- Mal-PEG6-COOH
- Mal-PEG5-CH2CH2Mal
- Mal-PEG4-Val-Cit-PAB-OH
- 1-(14-Hydroxy-3,6,9,12-tetraoxatetradecyl)-1H-pyrrole-2,5-dione
- 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(1H-pyrrole-2,5-dione)
- Mal-PEG5-amine TFA salt
- Mal-PEG4-Val-Cit-PAB-PNP