Clonixin Chemical Properties

Melting point:

233-235°

Boiling point:

410.2±45.0 °C(Predicted)

Density 

1.3230 (rough estimate)

refractive index 

1.5270 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO: soluble15mg/mL, clear

form 

powder

pka

1.69±0.36(Predicted)

color 

white to beige

Merck 

14,2392

CAS DataBase Reference

17737-65-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

36/37

WGK Germany 

3

RTECS 

QT0960000

HS Code 

2933.39.9200

Toxicity

LD50 in male mice, rats (mg/kg): 415, 335 orally; 198, 148 i.p.; 296, 325 s.c. (Tanaka)

Clonixin Usage And Synthesis

Uses

Analgesic.

Uses

Clonixin is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory actions. The compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.

Definition

ChEBI: A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a (2-methyl-3-chlorophenyl)amino group. Used (as its lysine salt) for treatment of renal colic, muscular pain and moderately severe migraine attacks.

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