(+/-)-alpha-Lipoamide Chemical Properties

Melting point:

127-129 °C(lit.)

Boiling point:

399.2±11.0 °C(Predicted)

Density 

1.1989 (rough estimate)

refractive index 

1.5364 (estimate)

storage temp. 

Sealed in dry,2-8°C

solubility 

Dichloromethane (Slightly), DMSO (Slightly, Heated, Sonicated), Ethanol (Slightly)

pka

16.59±0.40(Predicted)

form 

Solid

color 

Pale Yellow to Yellow

CAS DataBase Reference

940-69-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

JP1185000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(+/-)-alpha-Lipoamide Usage And Synthesis

Uses

(±)-α-Lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. When used in combination with Alprostadil, it has shown to have a good therapeutic effect on early diabetic nephropathy.

Definition

ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia.

storage

Store at -20°C

Purification Methods

DL--Lipoamide is recrystallised from EtOH and has UV with max 331nm in MeOH. [Reed et al. J Biol Chem 232 143 1958, IR: Wagner et al. J Am Chem Soc 78 5079 1956, Beilstein 19/7 V 238.]

(+/-)-alpha-Lipoamide(940-69-2)Related Product Information

• Glycine
• DL-Malic acid
• Acrylamide
• Folic acid
• Diethylstilbestrol
• α-Lipoic Acid
• Sulfamide
• Fomesafen
• Polyacrylamide
• Boc-D-Glutamine
• Ethyl 2-(Chlorosulfonyl)acetate
• N,N-Dimethylformamide
• Polyamide
• Lipoic acid
• DIAPHORASE
• ALPHA-LIPOAMIDE,DL-ALPHA-LIPOAMIDE
• (+/-)-alpha-Lipoamide
• phosphoric acid