Thalidomide-linker 6 Chemical Properties

storage temp. 

2-8°C, sealed storage, away from moisture

solubility 

Soluble in DMSO

form 

Solid

color 

White to off-white

Thalidomide-linker 6 Usage And Synthesis

Uses

Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556. DOI:10.1073/pnas.93.15.7552

Thalidomide-linker 6(2341840-99-9)Related Product Information

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• Thalidomide-NH-C4-NH2 TFA
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• Thalidomide-O-C6-NH2
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