N,N-Dibenzylhydroxylamine Chemical Properties

Melting point:

125-128 °C (lit.)

Boiling point:

353.27°C (rough estimate)

Density 

1.0439 (rough estimate)

refractive index 

1.5300 (estimate)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

Water Solubility 

Insoluble in water

form 

powder to crystal

pka

13.19±0.69(Predicted)

color 

White to Almost white

BRN 

978234

CAS DataBase Reference

621-07-8(CAS DataBase Reference)

NIST Chemistry Reference

Hydroxylamine, n,n-dibenzyl-,(621-07-8)

EPA Substance Registry System

Benzenemethanamine, N-hydroxy-N-(phenylmethyl)- (621-07-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

TSCA 

Yes

HS Code 

2928.00.2500

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

N,N-Dibenzylhydroxylamine Usage And Synthesis

Chemical Properties

white to slightly yellow adhering crystalline

Uses

N,N-Dibenzylhydroxylamine, upon oxidation, yields N-benzyl-α-phenylnitrone, which can undergo cycloaddition reaction with suitable dipolarophiles. It can be used to synthesize N,N,O-trisubstituted hydroxylamines and arylamines.

Preparation

A mixture of 14 gm (0.202 mole) of hydroxylamine hydrochloride and 50 gm (0.395 mole) of benzyl chloride in 200 ml of 70% ethanol is treated with 60 gm of crystalline sodium carbonate. The mixture is heated under a reflux condenser for 2 hr, cooled to room temperature, filtered, and the solids discarded. The filtrate is treated with sufficient ice water to cause precipitation of A^N-dibenzylhydroxylamine. The reaction mixture is then thoroughly cooled in a freezing mixture to permit complete precipitation of product to take place. The yield, upon filtration, is 26 gm (61.5%), m.p. 123°C. A similar preparation has recently been reported [13a].

N,N-Dibenzylhydroxylamine(621-07-8)Related Product Information

• Benzyl chloride
• Hydroxylamine sulfate
• Hydroxylamine hydrochloride
• METARAMINOL
• Dibenzylideneacetone
• N,N-Diethylhydroxylamine
• Benzyltrimethylammonium chloride
• Benzyltriethylammonium chloride
• Phenylacetone
• DIBENZYL SULFONE
• HYDROXYLAMINE
• 2,5-DIBENZYL-3-PHENYLDIHYDRO-2H-PYRROLO[3,4-D]ISOXAZOLE-4,6(3H,5H)-DIONE
• 2-BENZYL-3-PHENYL-4-(PHENYLSULFONYL)TETRAHYDROISOXAZOLE
• N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE
• N,N-BIS(2-CHLORO-6-FLUOROBENZYL)HYDROXYLAMINE
• N,N-Dibenzylhydroxylamine
• 3-HYDROXY-2-PHENYL-3,4-DIHYDROQUINAZOLIN-4-ONE
• N-[(2-CHLOROACETYL)OXY]-N,N-BIS(4-CHLOROBENZYL)AMINE