4-Methyl-1,2,3-thiadiazole-5-carboxylic acid Chemical Properties

Melting point:

169-173 °C (D)

Boiling point:

315.2±34.0 °C(Predicted)

Density 

1.530±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Aqueous Base (Slightly), DMSO

form 

Solid

pka

1.33±0.37(Predicted)

color 

Off-White

InChI

1S/C4H4N2O2S/c1-2-3(4(7)8)9-6-5-2/h1H3,(H,7,8)

InChIKey

NHHQOYLPBUYHQU-UHFFFAOYSA-N

SMILES

Cc1nnsc1C(O)=O

CAS DataBase Reference

18212-21-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29349990

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:ALFA

4-Methyl-1,2,3-thiadiazole-5-carboxylic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

4-Methyl-1,2,3-thiadiazole-5-carboxylic Acid can be used as agrochemical antiviral agents, fungicides, and insecticides.

Synthesis

To a methanolic solution of sodium hydroxide (3 mol/L, 80 mL) was added ethyl 4-methyl-1,2,3-thiadiazole-5-carboxylate (34.4 g, 0.15 mol) in one portion and the resulting mixture was then stirred for 12 hours at room temperature. Methanol was then removed by vacuum distillation and the remaining sodium salt was dissolved in purified water (200 mL) and acidified with dilute hydrochloric acid, adjusting the pH to 2-3 and then stirred and filtered for one hour, after which the solids were washed with n-hexane to give the product as a white solid (27.1 g) in 94% yield. mp168-170.1H NMR (300 MHz, CDCl3): ??2.86 ( s,3H,CH3-C-N). .

4-Methyl-1,2,3-thiadiazole-5-carboxylic acid(18212-21-0)Related Product Information

• 2-Chloro-5-chloromethylpyridine
• Methyl salicylate
• Bensulfuron methyl
• 2,5-Dimethylpyridine
• METSULFURON METHYL
• 5-Amino-2-methylpyridine
• Kresoxim-methyl
• 2-Mercapto-5-methyl-1,3,4-thiadiazole
• Thiophanate-methyl
• Methyl
• Methyl bromide
• 4-PHENYL-1,2,3-THIADIAZOLE-5-CARBOXYLIC ACID
• 4-Methyl-1,2,3-thiadiazole-5-carboxylic acid ethyl ester
• 1,2,3-Thiadiazole-5-carboxylic acid
• METHYL 4-ISOPROPYL-1,2,3-THIADIAZOLE-5-CARBOXYLATE
• 3-(TRIFLUOROMETHYL)PHENYL 4-METHYL-1,2,3-THIADIAZOLE-5-CARBOXYLATE
• 4-propyl-1,2,3-thiadiazole-5-carboxylic acid
• 1,2,3-Thiadiazole-5-carboxylicacid,4-(1-methylethyl)-(9CI)