Bis-propargyl-PEG10 Chemical Properties

Boiling point:

562.1±45.0 °C(Predicted)

Density 

1.079±0.06 g/cm3(Predicted)

Bis-propargyl-PEG10 Usage And Synthesis

Uses

Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-PEG10 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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