Hydroxy-PEG16-t-butyl ester
Hydroxy-PEG16-t-butyl ester Basic information
- Product Name:
- Hydroxy-PEG16-t-butyl ester
- Synonyms:
-
- Hydroxy-PEG16-t-butyl ester ISO 9001：2015 REACH
- 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49-Hexadecaoxahenpentacontanoic acid, 51-hydroxy-, 1,1-dimethylethyl ester
- tert-Butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-hexadecaoxahenpentacontan-51-oate
- tert-butyl 42-(2-hydroxyethyl)-1-(l1-oxidaneyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42l3,45-pentadecaoxaoctatetracontan-48-oate
- CAS:
- 2592433-80-0
- MF:
- C39H78O19
- MW:
- 851.03
- Mol File:
- 2592433-80-0.mol
More
Less
Hydroxy-PEG16-t-butyl ester Chemical Properties
- Boiling point:
- 774.9±55.0 °C(Predicted)
- Density
- 1.097±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
More
Less
Hydroxy-PEG16-t-butyl ester Usage And Synthesis
Uses
Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Hydroxy-PEG16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs; Alkyl/ether
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Hydroxy-PEG16-t-butyl esterSupplier
Xi'an Confluore Biological Technology Co., Ltd.
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
Dideu Industries Group Limited
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
Xiamen Sinopeg Biotech Co., Ltd.
- Tel
- 400-9189898 17359873007
- sales@sinopeg.com
Bide Pharmatech Ltd.
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
More
Less
Hydroxy-PEG16-t-butyl ester(2592433-80-0)Related Product Information
- OH-PEG6-CH2-COOMe
- Hydroxy-PEG6-ethyl ester
- TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
- OH-PEG7-CH2-COOMe
- HO-PEG10-tBu
- Hydroxy-PEG9-ethyl ester
- PEG4-COOME
- Hydroxy-PEG12-Boc
- Hydroxy-PEG3-ethyl ester
- PEG7-t-butly ester
- Hydroxy-PEG7-ethyl ester
- HO-PEG12-COOMe
- OH-PEG12-CH2-COOMe
- Hydroxy-PEG12-ethyl ester
- Hydroxy-PEG11-ethyl ester
- OH-PEG11-CH2-COOMe
- Hydroxy-PEG10-ethyl ester
- OH-PEG10-CH2-COOMe