ChemicalBook > CAS DataBase List > N-Methyl-1H-Indole-5-EthaneSulphonamide

N-Methyl-1H-Indole-5-EthaneSulphonamide

Product Name
N-Methyl-1H-Indole-5-EthaneSulphonamide
CAS No.
98623-50-8
Chemical Name
N-Methyl-1H-Indole-5-EthaneSulphonamide
Synonyms
2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide;ratriptanImpurity5;N-Methyl-1H-Indole-5-EthaneSulphomide;N-Methyl-1H-indole-5-ethanesulfonamide;N-Methyl-1H-Indole-5-EthaneSulphonamide;1H-Indole-5-ethanesulfonamide, N-methyl-;2-(1H-indol-5-yl)-N-MethylethanesulfonaMide;N-Methyl-1H-indole-5-ethanesulfonamide, >=98%;2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide;2-(1H-Indol-5-yl) -ethanesulfonic acid methyl amide
CBNumber
CB01023956
Molecular Formula
C11H14N2O2S
Formula Weight
238.31
MOL File
98623-50-8.mol
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N-Methyl-1H-Indole-5-EthaneSulphonamide Property

Melting point:
124-125°C
Boiling point:
458.4±47.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
11.52±0.40(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M313525
Product name
N-Methyl-1H-indole-5-ethanesulfonamide
Packaging
500mg
Price
$180
Updated
2021/12/16
TRC
Product number
M313525
Product name
N-Methyl-1H-indole-5-ethanesulfonamide
Packaging
2.5g
Price
$675
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0294434
Product name
N-METHYL-1H-INDOLE-5-ETHANE SULFONAMIDE
Purity
98.00%
Packaging
25G
Price
$2106.72
Updated
2021/12/16
aablocks
Product number
AA005TYY
Product name
N-Methyl-1h-indole-5-ethanesulfonamide
Purity
97%
Packaging
100mg
Price
$95
Updated
2021/12/16
AHH
Product number
MT-57055
Product name
N-Methyl-1H-indole-5-ethanesulfonamide
Purity
98%
Packaging
25g
Price
$770
Updated
2021/12/16
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N-Methyl-1H-Indole-5-EthaneSulphonamide Chemical Properties,Usage,Production

Uses

N-Methyl-1H-indole-5-ethanesulfonamide is used as a reagent in the synthesis of Naratriptan Hydrochloride (N378730); a triptan drug used for the treatment of migraine headaches.

General Description

N-Methyl-1H-Indole-5-EthaneSulphonamide, also known as 2-(1H-Indol-5-yl)-N-methylethanesulfonamide, is a white solid.

Synthesis

At 40-45 ℃ (hydrogen pressure: 3-4 kg/cm2), 2-(3-Phenylsulf-anyl-1H-indol-5-yl)-ethanesulfonic acidmethylamide (14) (5 g, 0.014 mol) was hydrogenated in ethanol: water (7:3) (40 ml) in an autoclave for 10 h. After that, the reaction mass was cooled to room temperature, followed by removing the catalyst through filtering. The filtrate was distilled out to get N-Methyl-1H-Indole-5-EthaneSulphonamide. 

N-Methyl-1H-Indole-5-EthaneSulphonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Methyl-1H-Indole-5-EthaneSulphonamide manufacturers

Career Henan Chemical Co
Product
N-Methyl-1H-Indole-5-EthaneSulphonamide 98623-50-8
Price
US $1.00/g
Min. Order
1g
Purity
97%
Supply Ability
100kg
Release date
2020-01-09

98623-50-8, N-Methyl-1H-Indole-5-EthaneSulphonamideRelated Search:

N-METHYL-N-[3-(TRIFLUOROMETHYL)BENZYL]AMINE N-METHYL-2-NITROBENZYLAMINE 3-METHOXY-N-METHYLBENZYLAMINE 97 N-METHYL-N-[4-(TRIFLUOROMETHYL)BENZYL]AMINE N-Methyl-3,4-dimethylbenzylamine 1-METHYL-1H-INDOLE-2-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER N-Methyl-2,3-difluorobenzylaMine N-Methyl-2-thiazolamine (4-FLUORO-BENZYL)-METHYL-AMINE 4-(Methylaminomethyl)benzonitrile (4-BROMOBENZYL)METHYLAMINE N-methylbiphenyl-2-amine N-Methyl-1-amino-hex-5-ene N-Methyl-N-(4-methylbenzyl)amine N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE Naratriptan Hydrochloride N-Methyl-1H-Indole-5-EthaneSulphonamide Naratriptan

  • N-Methyl-1H-Indole-5-EthaneSulphonamide
  • N-Methyl-1H-indole-5-ethanesulfonamide
  • 2-(1H-indol-5-yl)-N-MethylethanesulfonaMide
  • N-Methyl-1H-indole-5-ethanesulfonamide, >=98%
  • N-Methyl-1H-Indole-5-EthaneSulphomide
  • 1H-Indole-5-ethanesulfonamide, N-methyl-
  • 2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide
  • 2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide
  • ratriptanImpurity5
  • N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide)
  • 2-(1H-Indol-5-yl) -ethanesulfonic acid methyl amide
  • 98623-50-8