3-METHOXY-N-METHYLBENZYLAMINE 97

Product Name: 3-METHOXY-N-METHYLBENZYLAMINE 97
CAS No.: 41789-95-1
Chemical Name: 3-METHOXY-N-METHYLBENZYLAMINE 97
Synonyms: 3-METHOXY-N-METHYLBE;Diclofensine Impurity 1;(3-methoxybenzyl)methylamine;N-Methyl-3-MethoxybenzylaMine;3-Methoxy-N-methylbenzylamine;3-METHOXY-N-METHYLBENZYLAMINE 97;N-(3-METHOXYBENZYL)-N-METHYLAMINE;3-Methoxy-N-methylbenzylamine;(3-Methoxyphenyl)-N-MethylMethanaMine;3-Methoxy-1-(MethylaMinoMethyl)benzene
CBNumber: CB6498753
Molecular Formula: C9H13NO
Formula Weight: 151.21
MOL File: 41789-95-1.mol

More

Less

3-METHOXY-N-METHYLBENZYLAMINE 97 Property

Boiling point:: 130-133 °C28 mm Hg(lit.)
Density: 1.014 g/mL at 25 °C(lit.)
refractive index: n20/D 1.5290(lit.)
Flash point:: 212 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in chloroform, dichloromethane, ethyl acetate and methanol.
pka: 9.65±0.10(Predicted)
form: Liquid
Sensitive: Air Sensitive
InChIKey: FIFKRPFWLHBMHL-UHFFFAOYSA-N

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-41-43
Safety Statements: 26-36/37/39
WGK Germany: 2
HazardClass: IRRITANT
HS Code: 2922290090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 631124
Product name: 3-Methoxy-N-methylbenzylamine
Purity: 97%
Packaging: 1g
Price: $74.5
Updated: 2023/01/07

Sigma-Aldrich

Product number: 631124
Product name: 3-Methoxy-N-methylbenzylamine
Purity: 97%
Packaging: 5g
Price: $203
Updated: 2023/01/07

TRC

Product number: M263500
Product name: 3-Methoxy-N-methylbenzylamine
Packaging: 1g
Price: $55
Updated: 2021/12/16

TRC

Product number: M263500
Product name: 3-Methoxy-N-methylbenzylamine
Packaging: 500mg
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: 5753AB
Product name: 1-(3-Methoxyphenyl)-N-methylmethanamine
Packaging: 250mg
Price: $82
Updated: 2021/12/16

More

Less

3-METHOXY-N-METHYLBENZYLAMINE 97 Chemical Properties,Usage,Production

Chemical Properties

Liquid

Uses

3-Methoxy-N-methylbenzylamine is used as an intermediate in the synthesis of diclofensine hydrochloride.

Synthesis

591-31-1

74-89-5

41789-95-1

To a solution of 3-methoxybenzaldehyde (180 g, 1.32 mol) in methanol (1 L) was slowly added 40% aqueous methylamine (113 mL, 1.31 mol), and the reaction mixture was stirred at 0 °C for 1 hour. Subsequently, sodium borohydride (75 g, 1.98 mol) was added in batches at the same temperature and stirring was continued for 1 hour. Upon completion of the reaction, the solution was concentrated under reduced pressure to a smaller volume, diluted with water (200 mL) and extracted with dichloromethane (3 x 500 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product N-methyl-3-methoxybenzylamine (220 g, quantitatively) as a clear oil, which was used directly in the subsequent reaction without further purification.1H NMR (CDCl3, 500 MHz) δ: 7.23 (t, J = 8.0 Hz, 1H), 6.92-6.88 (m, 2H), 6.81-6.78 (m, 2H), 6.81-6.78 (m, 2H), 6.81-6.78 (m, 2H). 6.81-6.78 (m, 1H), 3.80 (s, 3H), 3.73 (s, 2H), 2.45 (s, 3H), 2.07 (br s, 1H).

References

[1] Patent: WO2010/132437, 2010, A1. Location in patent: Page/Page column 74; 101-102
[2] Patent: WO2009/149258, 2009, A2. Location in patent: Page/Page column 19; 23
[3] Patent: US2007/21408, 2007, A1. Location in patent: Page/Page column 57; 59; 60; 62; 63; 64-65; 66; 70; 71; 73; 74; 88
[4] Patent: US2014/275101, 2014, A1. Location in patent: Paragraph 0072; 0074; 0075
[5] Synthesis, 1990, # 3, p. 253 - 255

3-METHOXY-N-METHYLBENZYLAMINE 97 Preparation Products And Raw materials

Raw materials

Methylamine 3-METHOXY-N-METHYLBENZYLAMINE Sodium borohydride 3-Methoxybenzaldehyde

Preparation Products

More

Less

3-METHOXY-N-METHYLBENZYLAMINE 97 Suppliers

Canada 1 China 90 India 4 Switzerland 1 Ukraine 2 United States 11 Global 109

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

Sci General Material & Chemical Ltd

Tel: 021-58388037;21-58388037 13472507714
Email: 35177634@qq.com;1589045147@qq.com
Country: China
ProdList: 803
Advantage: 55

41789-95-1, 3-METHOXY-N-METHYLBENZYLAMINE 97Related Search:

N-Methylbenzylamine N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE N-Methyl-4-bromobenzylamine Hydrochloride 4-(Methylaminomethyl)benzonitrile (4-FLUORO-BENZYL)-METHYL-AMINE N-Methyl-3,4-dimethylbenzylamine N-METHYL-2-NITROBENZYLAMINE 3-(methylaminomethyl)benzonitrile 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride D-TUBOCURARINE CHLORIDE 2-METHOXY-N-METHYLBENZYLAMINE 97 N-(4-Methoxybenzyl)-N-methylamine DL-LAUDANOSINE 1-Benzylpiperazine Protopine Capsaicin Actinomycin D 3-Methoxybenzylamine

3-METHOXY-N-METHYLBE

(3-methoxybenzyl)methylamine(SALTDATA: FREE)

[(3-Methoxyphenyl)Methyl](Methyl)aMine

(3-Methoxyphenyl)-N-MethylMethanaMine

3-Methoxy-1-(MethylaMinoMethyl)benzene

N-Methyl-1-[3-(Methoxy)phenyl]MethanaMine

N-Methyl-3-MethoxybenzylaMine

(3-methoxybenzyl)methylamine hydrochloride

BENZENEMETHANAMINE, 3-METHOXY-N-METHYL-

3-METHOXY-N-METHYLBENZYLAMINE 97

(3-methoxybenzyl)methylamine

1-(3-methoxyphenyl)-N-methylmethanamine

3-Methoxy-N-methylbenzylamine

N-(3-METHOXYBENZYL)-N-METHYLAMINE

Diclofensine Impurity 1

3-Methoxy-<i>N</i>-methylbenzylamine

41789-95-1

Amines

C9 to C10

Nitrogen Compounds