ChemicalBook > CAS DataBase List > Quinazoline, 4-[(4-bromophenyl)methoxy]-

Quinazoline, 4-[(4-bromophenyl)methoxy]-

Product Name
Quinazoline, 4-[(4-bromophenyl)methoxy]-
CAS No.
737818-56-3
Chemical Name
Quinazoline, 4-[(4-bromophenyl)methoxy]-
Synonyms
WAY-340935;VEGFR2-IN-2;WAY-340935(VEGFR2-IN-2);VEGFR2-IN-2, 10 mM in DMSO;4-((4-Bromobenzyl)oxy)quinazoline;Quinazoline, 4-[(4-bromophenyl)methoxy]-;Inhibitor,WAY340935,Vascular endothelial growth factor receptor,WAY 340935,inhibit,VEGFR,Anticancer
CBNumber
CB010696756
Molecular Formula
C15H11BrN2O
Formula Weight
315.16
MOL File
737818-56-3.mol
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Quinazoline, 4-[(4-bromophenyl)methoxy]- Property

Boiling point:
455.0±25.0 °C(Predicted)
Density 
1.494±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 63 mg/mL (199.90 mM);Ethanol: 3 mg/mL (9.52 mM)
pka
2.66±0.30(Predicted)
form 
Solid
color 
White to off-white
Water Solubility 
Water: Insoluble
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Hazard and Precautionary Statements (GHS)

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Quinazoline, 4-[(4-bromophenyl)methoxy]- Chemical Properties,Usage,Production

Biological Activity

WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein.

References

[1] Sun J, et al. Org Biomol Chem. 2013 Nov 28;11(44):7676-86.

Quinazoline, 4-[(4-bromophenyl)methoxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

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