2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
- Product Name
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
- CAS No.
- 886497-81-0
- Chemical Name
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
- Synonyms
- 2-Formyl-4-(trifluoromethoxy)fluorobenzene;2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%;Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-;2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%
- CBNumber
- CB01119530
- Molecular Formula
- C8H4F4O2
- Formula Weight
- 208.11
- MOL File
- 886497-81-0.mol
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Property
- Boiling point:
- 200℃
- Density
- 1.428
- Flash point:
- 73℃
- refractive index
- 1.4430
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- liquid
- color
- Clear, colourless
- Water Solubility
- Slightly miscible with water.
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 886497-81-0
Safety
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F599170
- Product name
- 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC1092
- Product name
- 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 2615-3-42
- Product name
- 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- PC1092
- Product name
- 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- 2615-3-42
- Product name
- 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
- Purity
- 98%
- Packaging
- 5G
- Price
- $92
- Updated
- 2021/12/16
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Chemical Properties,Usage,Production
Uses
2-Fluoro-5-(trifluoromethoxy)benzaldehyde is used as a precursor for organic synthesis. It is also used as a pharmaceutical intermediate.
Synthesis
352-67-0
68-12-2
886497-81-0
Example 49 3-Trifluoromethoxy-10-methyl-9H-imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine was synthesized as follows: a) Preparation of 2-fluoro-5-(trifluoromethoxy)benzaldehyde: 1-fluoro-4-(trifluoromethoxy)benzene (21.0 g, 117 mmol) was dissolved in tetrahydrofuran (THF, 233 mL) under dry conditions, and cooled to 4°C. A hexane solution of n-butyllithium (n-BuLi) was slowly added and the reaction temperature was kept below 10°C. The reaction mixture was ether The reaction mixture was extracted with ethyl ether and the organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. After concentration under reduced pressure, it was purified by silica gel column chromatography (eluent: heptane/ethyl acetate=100:0 to 80:2) to obtain 2-fluoro-5-(trifluoromethoxy)benzaldehyde (11.0 g, yield 53%) as a light yellow oil. 1H-NMR (300 MHz, DMSO-d6): δ=7.60 (t, J=9.2 Hz, 1H), 7.75-7.85 (m, 2H), 10.20 (s, 1H).
References
[1] Patent: US2006/128691, 2006, A1. Location in patent: Page/Page column 23-24
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE manufacturers
- Product
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2025-03-14
- Product
- 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-10