ChemicalBook > CAS DataBase List > 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE

2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE

Product Name: 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
CAS No.: 886497-81-0
Chemical Name: 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
Synonyms: 2-Formyl-4-(trifluoromethoxy)fluorobenzene;2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%;Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-;2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%
CBNumber: CB01119530
Molecular Formula: C8H4F4O2
Formula Weight: 208.11
MOL File: 886497-81-0.mol

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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Property

Boiling point:: 200℃
Density: 1.428
Flash point:: 73℃
refractive index: 1.4430
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: liquid
color: Clear, colourless
Water Solubility: Slightly miscible with water.
Sensitive: Air Sensitive
CAS DataBase Reference: 886497-81-0

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Safety

HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: F599170
Product name: 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC1092
Product name: 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity: 98%
Packaging: 1g
Price: $35
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-3-42
Product name: 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity: 98%
Packaging: 1g
Price: $39
Updated: 2021/12/16

Apolloscientific

Product number: PC1092
Product name: 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity: 98%
Packaging: 5g
Price: $83
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-3-42
Product name: 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity: 98%
Packaging: 5G
Price: $92
Updated: 2021/12/16

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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-Fluoro-5-(trifluoromethoxy)benzaldehyde is used as a precursor for organic synthesis. It is also used as a pharmaceutical intermediate.

Synthesis

352-67-0

68-12-2

886497-81-0

Example 49 3-Trifluoromethoxy-10-methyl-9H-imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine  was synthesized as follows: a) Preparation of 2-fluoro-5-(trifluoromethoxy)benzaldehyde: 1-fluoro-4-(trifluoromethoxy)benzene (21.0 g, 117 mmol) was dissolved in tetrahydrofuran (THF, 233 mL) under dry conditions, and cooled to 4°C. A hexane solution of n-butyllithium (n-BuLi) was slowly added and the reaction temperature was kept below 10°C. The reaction mixture was ether The reaction mixture was extracted with ethyl ether and the organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. After concentration under reduced pressure, it was purified by silica gel column chromatography (eluent: heptane/ethyl acetate=100:0 to 80:2) to obtain 2-fluoro-5-(trifluoromethoxy)benzaldehyde (11.0 g, yield 53%) as a light yellow oil. 1H-NMR (300 MHz, DMSO-d6): δ=7.60 (t, J=9.2 Hz, 1H), 7.75-7.85 (m, 2H), 10.20 (s, 1H).

References

[1] Patent: US2006/128691, 2006, A1. Location in patent: Page/Page column 23-24

2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-14

Career Henan Chemical Co

Product: 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-10

886497-81-0, 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Related Search:

2-FLUORO-5-METHOXYBENZALDEHYDE 2-FLUORO-5-HYDROXYBENZALDEHYDE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 4-FLUORO-3-METHYLANISOLE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZAMIDE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZOIC ACID 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE 4-(Trifluoromethoxy)fluorobenzene

2-Formyl-4-(trifluoromethoxy)fluorobenzene

2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%

Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-

2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%

886497-81-0