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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE

Product Name
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
CAS No.
886497-81-0
Chemical Name
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE
Synonyms
2-Formyl-4-(trifluoromethoxy)fluorobenzene;2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%;Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-;2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%
CBNumber
CB01119530
Molecular Formula
C8H4F4O2
Formula Weight
208.11
MOL File
886497-81-0.mol
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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Property

Boiling point:
200℃
Density 
1.428
Flash point:
73℃
refractive index 
1.4430
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
liquid
color 
Clear, colourless
Water Solubility 
Slightly miscible with water.
Sensitive 
Air Sensitive
CAS DataBase Reference
886497-81-0
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Safety

HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
F599170
Product name
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Packaging
50mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
PC1092
Product name
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity
98%
Packaging
1g
Price
$35
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-3-42
Product name
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity
98%
Packaging
1g
Price
$39
Updated
2021/12/16
Apolloscientific
Product number
PC1092
Product name
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity
98%
Packaging
5g
Price
$83
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-3-42
Product name
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
Purity
98%
Packaging
5G
Price
$92
Updated
2021/12/16
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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-Fluoro-5-(trifluoromethoxy)benzaldehyde is used as a precursor for organic synthesis. It is also used as a pharmaceutical intermediate.

Synthesis

352-67-0

68-12-2

886497-81-0

Example 49 3-Trifluoromethoxy-10-methyl-9H-imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine  was synthesized as follows: a) Preparation of 2-fluoro-5-(trifluoromethoxy)benzaldehyde: 1-fluoro-4-(trifluoromethoxy)benzene (21.0 g, 117 mmol) was dissolved in tetrahydrofuran (THF, 233 mL) under dry conditions, and cooled to 4°C. A hexane solution of n-butyllithium (n-BuLi) was slowly added and the reaction temperature was kept below 10°C. The reaction mixture was ether The reaction mixture was extracted with ethyl ether and the organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. After concentration under reduced pressure, it was purified by silica gel column chromatography (eluent: heptane/ethyl acetate=100:0 to 80:2) to obtain 2-fluoro-5-(trifluoromethoxy)benzaldehyde (11.0 g, yield 53%) as a light yellow oil. 1H-NMR (300 MHz, DMSO-d6): δ=7.60 (t, J=9.2 Hz, 1H), 7.75-7.85 (m, 2H), 10.20 (s, 1H).

References

[1] Patent: US2006/128691, 2006, A1. Location in patent: Page/Page column 23-24

2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Suppliers

China 96 India 1 United Kingdom 3 United States 9 Global 109
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2025-03-14
Career Henan Chemical Co
Product
2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 886497-81-0
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-10

886497-81-0, 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE Related Search:

2-FLUORO-5-METHOXYBENZALDEHYDE 2-FLUORO-5-HYDROXYBENZALDEHYDE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE 4-FLUORO-3-METHYLANISOLE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZAMIDE 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZOIC ACID 2-FLUORO-5-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE 4-(Trifluoromethoxy)fluorobenzene

  • 2-Formyl-4-(trifluoromethoxy)fluorobenzene
  • 2-Fluoro-5-(trifluoromethoxy)benzaldehyde98%
  • Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-
  • 2-Fluoro-5-(trifluoromethoxy)benzaldehyde97%
  • 886497-81-0