ChemicalBook > CAS DataBase List > 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

Product Name
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
CAS No.
885518-49-0
Chemical Name
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
Synonyms
Methyl 6-bromo-(1H)-indaz...;6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER;6-BroMo-1H-indazol-4-carboxylic acid Methyl ester;6-BroMo-1H-indazole-4-carboxylic acid Methyl ester;1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester;1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI)
CBNumber
CB0128102
Molecular Formula
C9H7BrN2O2
Formula Weight
255.07
MOL File
Mol file
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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Property

Boiling point:
395.9±22.0 °C(Predicted)
Density 
1.709±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
11.21±0.40(Predicted)
Appearance
light yellow solid
InChI
InChI=1S/C9H7BrN2O2/c1-14-9(13)6-2-5(10)3-8-7(6)4-11-12-8/h2-4H,1H3,(H,11,12)
InChIKey
FEPRHRPOKPTRQZ-UHFFFAOYSA-N
SMILES
N1C2=C(C(C(OC)=O)=CC(Br)=C2)C=N1
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
J91322
Product name
Methyl6-bromo-1H-indazole-4-carboxylate
Packaging
1g
Price
$30
Updated
2021/12/16
SynQuest Laboratories
Product number
4H23-9-04
Product name
Methyl 6-bromo-1H-indazole-4-carboxylate
Purity
98%
Packaging
1g
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-B0755
Product name
methyl6-bromo-1H-indazole-4-carboxylate
Packaging
5g
Price
$62
Updated
2021/12/16
SynQuest Laboratories
Product number
4H23-9-04
Product name
Methyl 6-bromo-1H-indazole-4-carboxylate
Purity
98%
Packaging
5G
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J91322
Product name
Methyl6-bromo-1H-indazole-4-carboxylate
Packaging
5g
Price
$90
Updated
2021/12/16
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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 6-bromo-4-indazolecarboxylate is mainly used as an organic synthesis intermediate and is widely used in drug development and chemical research.

Synthesis

1346597-55-4

885518-49-0

Step 6: Synthesis of methyl 6-bromo-1H-indazole-4-carboxylate To a stirred solution of methyl 1-acetyl-6-bromo-1H-indazole-4-carboxylate (18 g, 61.0 mmol) in methanol (350 mL) was slowly added 6N HCl (350 mL). The reaction mixture was stirred at 60 °C for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Subsequently, the reaction mixture was alkalized with saturated NaHCO3 solution to pH 8. The precipitated solid was collected by filtration and dried under vacuum. The dried solid was stirred in ether for 15 min, filtered again and dried to give methyl 6-bromo-1H-indazole-4-carboxylate (11 g, 71.7% yield).

References

[1] Patent: WO2012/118812, 2012, A2. Location in patent: Page/Page column 313
[2] Patent: CN105037360, 2016, B. Location in patent: Paragraph 0400; 0401; 0402

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Suppliers

China 117 India 1 United Kingdom 1 United States 18 Global 137
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER manufacturers

Hebei Fengjia New Material Co., Ltd
Product
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 885518-49-0
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-08-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 885518-49-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-12-04
Shanghai Rlavie Technology Co ltd
Product
6-BroMo-4-indazolecarboxylic acid Methyl ester 885518-49-0
Price
US $0.00-0.00/kg
Min. Order
0.0001kg
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-10

885518-49-0, 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTERRelated Search:

Formic acid VINYL CHLORIDE methyl6-chloropyridazine-4-carboxylate METHYL 6-CHLOROPYRIDAZINE-3-CARBOXYLATE 6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 6-BROMO-(1H)INDAZOLE-4-CARBOXYLIC ACID 2-Chloro-6-pyrazinecarboxylic acid methyl ester 6-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER Methyl 6-bromo-2-naphthoate 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER methyl 6-methylpyridine-2-carboxylate 6-CHLORO-2-PICOLINIC ACID METHYL ESTER Methyl 6-chloronicotinate Methyl 6-bromohexanoate Methyl 6-bromoisoquinoline-1-carboxylate methyl 6-chloropyrimidine-4-carboxylate METHYL 6-FORMYLNICOTINATE Methyl 6-bromonicotinate

  • 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
  • 6-BroMo-1H-indazol-4-carboxylic acid Methyl ester
  • Methyl 6-bromo-(1H)-indaz...
  • 1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester
  • 6-BroMo-1H-indazole-4-carboxylic acid Methyl ester
  • 1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI)
  • 885518-49-0
  • Indazoles