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isoliquiritin apioside

Product Name
isoliquiritin apioside
CAS No.
120926-46-7
Chemical Name
isoliquiritin apioside
Synonyms
Neolicuroside;Soliquiritin apioside;isoliquiritin apioside;isoliquiritin apioside USP/EP/BP;Isoliquiritin apioside, 10 mM in DMSO;2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-;2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-;(2E)-3-[4-[(2-O-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-2-propen-1-one;(E)-3-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1-(2,4-dihydroxyphenyl)prop-2-en-1-one;(E)-3-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
CBNumber
CB01352511
Molecular Formula
C26H30O13
Formula Weight
550.51
MOL File
120926-46-7.mol
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isoliquiritin apioside Property

Boiling point:
901.0±65.0 °C(Predicted)
Density 
1.63
storage temp. 
-20°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.46±0.35(Predicted)
color 
Yellow to orange
biological source
plant
Water Solubility 
water: slightly soluble
InChIKey
VMMVZVPAYFZNBM-KVFWHIKKSA-N
SMILES
O([C@@H]1OC[C@]([C@H]1O)(O)CO)[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC1C=CC(=CC=1)/C=C/C(C1C=CC(=CC=1O)O)=O)CO)O)O
CAS DataBase Reference
120926-46-7
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB01065
Product name
Neolicuroside
Purity
≥85% (LC/MS-ELSD)
Packaging
1mg
Price
$382
Updated
2025/07/31
Usbiological
Product number
297261
Product name
Isoliquiritin apioside
Packaging
5mg
Price
$506
Updated
2021/12/16
Usbiological
Product number
300489
Product name
Isoliquiritin apioside
Packaging
10mg
Price
$546
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105367
Product name
Isoliquiritin apioside
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594042
Product name
Isoliquiritin apioside
Packaging
10mg
Price
$596.7
Updated
2021/12/16
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isoliquiritin apioside Chemical Properties,Usage,Production

Chemical Properties

White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice.

Uses

Isoliquiritin apioside can be used to resist myocardial ischemia and inhibit the proliferation of HIV.

Definition

ChEBI: Neolicuroside is a member of flavonoids and a glycoside.

Biological Activity

Neolicuroside modulates signaling pathways (e.g., MAPK, NF-KB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).

IC 50

MMP9; NF-κB; p38 MAPK

isoliquiritin apioside Preparation Products And Raw materials

Raw materials

Preparation Products

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isoliquiritin apioside Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from isoliquiritin apioside manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Isoliquiritin apioside 120926-46-7
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-02
Career Henan Chemical Co
Product
isoliquiritin apioside 120926-46-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

120926-46-7, isoliquiritin apiosideRelated Search:


  • isoliquiritin apioside
  • (2E)-3-[4-[(2-O-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-2-propen-1-one
  • Soliquiritin apioside
  • Neolicuroside
  • (E)-3-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
  • 2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-
  • isoliquiritin apioside USP/EP/BP
  • (E)-3-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-1-(2,4-dihydroxyphenyl)prop-2-en-1-one
  • Isoliquiritin apioside, 10 mM in DMSO
  • 2-Propen-1-one, 3-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-, (2E)-
  • 120926-46-7