Uses
ChemicalBook > CAS DataBase List > (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

Uses
Product Name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
CAS No.
866783-13-3
Chemical Name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
Synonyms
Ivabradine Impurity 17 HCl;(1R)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride;(7S)-3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride;(1S)-4;Ivabradine RC 6 (HCl);Ivebradine impurity 3;Ivabradine Impurity 85;Ivabradine Intermediate;Ivabradine intermediate1;Ivabradine Impurity 7 HCL
CBNumber
CB01455900
Molecular Formula
C12H18ClNO2
Formula Weight
243.73
MOL File
866783-13-3.mol
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(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Property

Melting point:
>216°C (dec.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1/C12H17NO2.ClH/c1-13-7-9-4-8-5-11(14-2)12(15-3)6-10(8)9;/h5-6,9,13H,4,7H2,1-3H3;1H/t9-;/s3
InChIKey
SWSAIQSQSDOONK-OVMXBOEKNA-N
SMILES
COC1=CC2[C@@H](CNC)CC=2C=C1OC.Cl |&1:5,r|
CAS DataBase Reference
866783-13-3(CAS DataBase Reference)
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Safety

HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D461760
Product name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride
Packaging
250mg
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD150184
Product name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride
Packaging
500mg
Price
$125
Updated
2021/12/16
AK Scientific
Product number
X0048
Product name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutanehydrochloride
Packaging
250mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD150184
Product name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride
Packaging
1g
Price
$200
Updated
2021/12/16
AK Scientific
Product number
X0048
Product name
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutanehydrochloride
Packaging
1g
Price
$250
Updated
2021/12/16
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(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Chemical Properties,Usage,Production

Uses

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride is an intermediate used in preparation of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.

Uses

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane is an intermediate used in preparation of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Suppliers

China 241 India 12 United Kingdom 2 United States 7 Global 262
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View Lastest Price from (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 866783-13-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
500kg/M
Release date
2023-09-06
Hangzhou ICH Biofarm Co., Ltd
Product
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 866783-13-3
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-09
Weijer International Trade (Hebei) Co., Ltd.
Product
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 866783-13-3
Price
US $13.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-08

866783-13-3, (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochlorideRelated Search:

Idarubicin hydrochloride Dimethylamine hydrochloride 4-AMINOAZOBENZENE HYDROCHLORIDE 4-Dimethylaminobenzaldehyde Dimethoxymethane Basic Violet 1 Methyl acrylate Tribenuron methyl Methyl salicylate Methanol D-Glucosamine hydrochloride Kresoxim-methyl Topotecan hydrochloride Methylparaben AMINOGUANIDINE HYDROCHLORIDE (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one Voriconazole Irinotecan hydrochloride

  • (1S)-4,5-Dimethoxy-1-(Methylaminomethyl)-Benzocyclobutane Hcl
  • (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
  • (7S)-3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride
  • (1S)-4,5-Dimethoxy-1-(methylaminoethyl)benzocyclobutane HCl
  • (S)-N-[(4,5-diMethoxybenzocyclobut-1-yl)Methyl ]-N-MethylaMine h
  • (S)-(4,5-diMethoxy-1,2-dihydrocyclobutabenzen-1-yl)MethanaMine
  • 3,4-diMethoxy-N-Methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-MethanaMine hydrochloride
  • Bicyclo[4.2.0]octa-1,3,5-triene-7-MethanaMine, 3,4-diMethoxy-N-Methyl-, hydrochloride
  • (1S)-4,5-DiMethoxy-1-[(MethylaMino)Methyl]benzocyclobutane
  • (1S)-4,5-DiMethoxy-1-[(MethylaMino)Methyl]benzoc
  • Ivabradine hydrochloride main chain
  • Ivabradine intermediate1
  • (S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine hydrochloride
  • {[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amine hydrochloride
  • (1S)-4
  • 5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
  • Ivabradine Impurity 85
  • Ivabradine related compound
  • Ivabradine related compound 12
  • (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocycl
  • 3,4-dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride (For Ivabradine)
  • [N-[[3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL] CARBONYL]-N-METHYLAMINE]
  • S-4,5-Dimethoxy-1-[(methylamino)methyl]benzo cyclobutane hydrochloride
  • (1R)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
  • (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochlorideY655
  • Ivabradine Impurity 17 HCl
  • (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride CAS 866783-13-3
  • (1S)-4,5-Dimethoxy-1-[(methylamine)methyl]benzocyclobutane HCl
  • (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane h...
  • Ivabradine RC 6 (HCl)
  • Ivabradine Impurity 7 HCL
  • Ivebradine impurity 3
  • Ivabradine Intermediate
  • 866783-13-3