Oxybutynin hydrochloride

Product Name: Oxybutynin hydrochloride
CAS No.: 1508-65-2
Chemical Name: Oxybutynin hydrochloride
Synonyms: Tropax;Cystrin;Dridase;Inobase;mj4309-1;ditropan;MJ 50-58;Pollakisu;Oxybutynin HC;OXYBUTYNIN HCL
CBNumber: CB0178112
Molecular Formula: C22H32ClNO3
Formula Weight: 393.95
MOL File: 1508-65-2.mol

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Oxybutynin hydrochloride Property

Melting point:: 122-124°C
storage temp.: room temp
solubility: H2O: soluble50mg/mL
form: powder
color: white
CAS DataBase Reference: 1508-65-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: GV2800000
HS Code: 29221990
Toxicity: LD50 orally in rats: 1220 mg/kg (Goldenthal)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2547
Product name: Oxybutynin Chloride
Packaging: 500MG
Price: $170
Updated: 2024/03/01

Sigma-Aldrich

Product number: O2881
Product name: Oxybutynin chloride
Purity: ≥98% (TLC), powder
Packaging: 1g
Price: $88.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1485103
Product name: Oxybutynin chloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Cayman Chemical

Product number: 23825
Product name: Oxybutynin (hydrochloride)
Purity: ≥98%
Packaging: 1g
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 23825
Product name: Oxybutynin (hydrochloride)
Purity: ≥98%
Packaging: 5g
Price: $210
Updated: 2024/03/01

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Oxybutynin hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Originator

Ditropan, Marion , US ,1975

Uses

An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells

Uses

anticholinergic

Uses

An antagonist of M1, M2, & M3 muscarinic acetylcholine receptors

Manufacturing Process

A mixture of 394.2 grams of methyl phenylcyclohexylglycolate and 293.1 grams of 4-diethylamino-2-butynyl acetate was dissolved with warming in 2.6 liters of n-heptane. The solution was heated with stirring to a temperature of 60° to 70°C and 8.0 grams of sodium methoxide were added. The temperature of the mixture was then raised until the solvent began to distill. Distillation was continued at a gradual rate and aliquots of the distillate were successively collected and analyzed for the presence of methyl acetate by measurement of the refractive index. The reaction was completed when methyl acetate no longer distilled, and the refractive index observed was that of pure heptane (nD26 = 1.3855). About 3? hours were required for the reaction to be completed.
The reaction mixture was then allowed to cool to room temperature, washed with water, and extracted with four 165 ml portions of 2 N hydrochloric acid. The aqueous extracts were combined and stirred at room temperature to permit crystallization of the hydrochloride salt of the desired product. Crystallization was completed by cooling the slurry in an ice bath, and the product was collected by filtration, pressed dry, and recrystallized from 750 ml of water. Yield of pure crystalline material, 323 grams.

brand name

Ditropan (ALZA).

Therapeutic Function

Spasmolytic

Biological Activity

oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

Biochem/physiol Actions

Muscarinic acetylcholine receptor antagonist; inhibits proliferation of bladder smooth muscle cells, perhaps by downregulation of growth promoting genes.

Clinical Use

Urinary frequency, urgency and incontinence
Neurogenic bladder instability and nocturnal enuresis

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. An eye irritant. Human systemic effects: coma, mydriasis, rate changes. An anticholinergic agent. When heated to decomposition it e

Drug interactions

Potentially hazardous interactions with other drugs
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.
Other antimuscarinic agents: increased antimuscarinic effects.

Metabolism

Oxybutynin undergoes extensive first-pass metabolism, particularly by the cytochrome P450 isoenzyme
CYP3A4. One of the metabolites, N-desethyloxybutynin is pharmacologically active.
Oxybutynin and its metabolites are excreted in the urine and faeces.

Oxybutynin hydrochloride Preparation Products And Raw materials

Raw materials

Cyclohexanol

Preparation Products

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Oxybutynin hydrochloride Suppliers

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View Lastest Price from Oxybutynin hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Oxybutynin hydrochloride 1508-65-2
Price: US $0.00/Kg/Bag
Min. Order: 100g
Purity: 99%-102%
Supply Ability: 10kgs
Release date: 2021-08-03

Shaanxi Dideu Medichem Co. Ltd

Product: Oxybutynin hydrochloride 1508-65-2
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-05-08

Hebei Yanxi Chemical Co., Ltd.

Product: Oxybutynin hydrochloride 1508-65-2
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-18

1508-65-2, Oxybutynin hydrochlorideRelated Search:

Triethylamine hydrochloride 1-AdaMantanethylaMine Glycolic acid Topotecan hydrochloride Buflomedil hydrochloride Oxybutynin Ethyltriphenylphosphonium bromide Cyclohexylamine hydrochloride Methyl cyclohexylphenylglycolate α-Descyclohexyl-α-phenyl Oxybutynin N-Desethyl-N-propyl Oxybutynin Oxybutynin IMpurity C OXYBUTYNIN IMPURITY A 2-Cyclohexylmandelic acid (S)-OXYBUTYNIN HYDROCHLORIDE Tramadol hydrochloride 2-Butyn-1-ol Sibutramine hydrochloride

OXYBUTYNIN HCL

OXYBUTYNIN HYDROCHLORIDE

OXYBUTYNIN CHLORIDE

A-PHENYLCYCLOHEXANEGLYCOLIC ACID 4-(DIETHYLAMINO)-2-BUTYNYL ESTER, HYDROCHLORIDE

4-diethylamino-2-butynylphenyl(cyclohexyl)glycolatehydrochloride

alpha-phenylcyclohexaneglycolicacid4-(diethylamino)-2-butynylesterhydroch

cyclohexaneglycolicacid,alpha-phenyl-,4-(diethylamino)-2-butynylester,hydr

ditropan

mj4309-1

oxibutininahydrochloride

α-phenylcyclohexaneglycolic acid 4-(diethylamino)-2-butynyl ester hydrochloride

2-Butyn-1-ol, 4-(diethylamino)-, a-phenylcyclohexaneglycolate (ester), hydrochloride (8CI)

4-(Diethylamino)-2-butynyl a-phenylcyclohexaneglycolate hydrochloride

Benzeneacetic acid, a-cyclohexyl-a-hydroxy-, 4-(diethylamino)-2-butynyl ester, hydrochloride (9CI)

Cyclohexaneglycolic acid, a-phenyl-, 4-(diethylamino)-2-butynyl ester, hydrochloride (7CI, 8CI)

Cystrin

Dridase

MJ 50-58

Pollakisu

Tropax

OXYBUTYNINE HCL

ALPHA-PHENYLCYCLOHEXANEGLYCOLIC ACID 4-(DIETHYLAMINO)-2-BUTYNYL ESTER HYDROCHLORIDE

4-(diethylamino)but-2-ynyl cyclohexylphenylglycolate hydrochloride

OXYBUTYNIN CHLORIDE USP

Inobase

Oxybutynin hydrochride

Oxybutynin(Ditropan) HCL

Oxybutynin chloride,α-Phenylcyclohexaneglycolic acid 4-(diethylamino)-2-butynyl ester hydrochloride

Oxybutynin Chloride (200 mg)H0E0800.998mg/mg(dr)

Oxybutynin Chloride (200 mg)

Qxybutynin hydrochloride

(±)-Oxybutynin-d11 HCl

Oxybutynin HC

Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, hydrochloride (1:1)

4-(diethylaMino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

4-(Diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

Oxybutynin hydrochloride CRS

4-(Diethylamino)-2-butyn-1-yl Cyclohexyl(hydroxy)phenylacetate Hydrochloride

4-(Diethylamino)-2-butynyl alpha-Phenylcyclohexaneglycolate Hydrochloride

alpha-Phenylcyclo

Cyclohexyl(hydroxy)phenylacetic Acid 4-(Diethylamino)-2-butyn-1-yl Ester Hydrochloride

Oxybutynin hydrochloride USP/EP/BP

Oxybutynin Chloride/ Hydrochloride

Oxybutynin HydrochlorideQ: What is Oxybutynin Hydrochloride Q: What is the CAS Number of Oxybutynin Hydrochloride Q: What is the storage condition of Oxybutynin Hydrochloride Q: What are the applications of Oxybutynin Hydrochloride

Oxybutynin Chloride (1485103)

Benzeneacetic acid, a-cyclohexyl-a-hydroxy-,4-(diethylamino)-2-butyn-1-yl ester, hydrochloride (1:1)

1508-65-2

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