5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine

Product Name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
CAS No.: 951626-91-8
Chemical Name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
Synonyms: 3-chloro-5-Bromo-7-azaindole;5-Bromo-3-chloro-7-azaindole;5-Bromo-3-chloro-7-azaindole 96%;5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-chloro-
CBNumber: CB02102230
Molecular Formula: C7H4BrClN2
Formula Weight: 231.48
MOL File: 951626-91-8.mol

More

Less

5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine Property

Melting point:: 216-220 °C
Density: 1.878±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 11.33±0.40(Predicted)
form: powder
Appearance: Off-white to pink Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-36/37/39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 702315
Product name: 5-Bromo-3-chloro-7-azaindole
Purity: 96%
Packaging: 1g
Price: $133
Updated: 2023/06/20

TRC

Product number: B701618
Product name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42501
Product name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 500mg
Price: $80
Updated: 2021/12/16

Matrix Scientific

Product number: 126588
Product name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
Purity: >95%
Packaging: 1g
Price: $108
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42501
Product name: 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 1g
Price: $120
Updated: 2021/12/16

More

Less

5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Usage,Production

Synthesis

183208-35-7

951626-91-8

The general procedure for the synthesis of 5-bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine from 5-bromo-7-azaindole was as follows: 0.50 g (2.54 mmol) of 5-bromo-1H-pyrrolo[2,3-b]pyridine was dissolved in 10 mL of N,N-dimethylformamide, followed by the addition of 0.37 g (2.79 mmol) of N-chloro-butanedi imide and 0.38 g (2.79 mmol) of dibenzoyl peroxide. The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, it was extracted with ethyl acetate and distilled water and the organic layer was concentrated under reduced pressure. The residue was purified by column chromatography to afford 0.50 g (85.0% yield) of the target compound 5-bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine.1H NMR (DMSO-d6) δ: 12.24 (br s, 1H), 8.35 (s, 1H), 8.14 (s, 1H), 8.03 (d, 1H), 7.81 (m, 1H ), 7.77 (s, 1H), 7.64 (t, 1H).

References

[1] Journal of Organic Chemistry, 2018, vol. 83, # 2, p. 930 - 938
[2] Patent: WO2016/129933, 2016, A2. Location in patent: Page/Page column 48

5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine Suppliers

China 52 India 1 Switzerland 1 United Kingdom 2 United States 7 Global 63

ITIC MEDCHEM(SUZHOU) CO.,LTD.

Tel: 0512-68323967 18015559028
Fax: +86-512-69200360
Email: sales@iticmedchem.com
Country: China
ProdList: 506
Advantage: 61

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 3993
Advantage: 55

Shanghai Devinchem Ltd

Tel: 027-65318838 13646286950
Email: sales@devinchem.com
Country: China
ProdList: 2953
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

ShangHai Yuchuan Pharmaceutical Technology Co., Ltd.

Tel: 02161555100
Fax: -
Country: China
ProdList: 820
Advantage: 58

Shanghai XinKai Chemical Technology Co., Ltd.

Tel: 021-58930698 15921516558
Fax: 86-021-58933679
Email: zhangyichao84@126.com
Country: China
ProdList: 981
Advantage: 55

951626-91-8, 5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridineRelated Search:

5-BROMO-3-IODO-1H-PYRROLO[2,3-B]PYRIDINE 5-BROMO-3-(BROMOMETHYL)PYRIDIN-2-AMINE HYDROBROMIDE 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE 5-BROMO-3-METHYL-1H-PYRAZOLE 5-BROMO-3-FORMYLINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 5-BROMO-3-CHLORO-1H-INDAZOLE 5-Bromo-3-cyanoindole 5-BroMo-3,3-diMethylindoline 5-Bromo-3-chlorophenylene-1,2-diamine, 5-Bromo-3-chloro-1,2-diaminobenzene 1H-Indole, 5-broMo-3-iodo- Methyl-5-bromo-2 pyrimidine carboxylate 5-BROMO-3-IODO-PYRIDIN-2-OL 5-BROMO-3-IODO-2-METHOXYPYRIDINE 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile 5-Bromo-2-hydroxy-3-(trifluoromethyl)pyridine 2-Amino-3-Difluoromethoxy-5-Bromopyridine 5-BroMo-3,4-dihydroisoquinolin-1(2H)-one Imidazole

5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine

5-Bromo-3-chloro-7-azaindole

5-Bromo-3-chloro-7-azaindole 96%

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-chloro-

3-chloro-5-Bromo-7-azaindole

951626-91-8

Heterocycle-Pyridine series