Formoterol fumarate dihydrate
- Product Name
- Formoterol fumarate dihydrate
- CAS No.
- 183814-30-4
- Chemical Name
- Formoterol fumarate dihydrate
- Synonyms
- Formoterol fumarate dihydrate;Unii-W34shf8J2k;Formoterol hemifumar;forMaMide fuMarate dihydrate;Formoterol Fumarate (100 mg);Formoterol fumarate 2-hydrate;Arformoterol Fumarate Dihydrate;Formoterol Hemifumarate Dihydrate;Formoterol hemifumarate monohydrate;Formoterol fumarate dihydrate, >=99%
- CBNumber
- CB02130563
- Molecular Formula
- C23H28N2O8
- Formula Weight
- 460.48
- MOL File
- 183814-30-4.mol
Formoterol fumarate dihydrate Property
- Melting point:
- 116-120°C
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL
- form
- solid
- color
- white to off-white
- InChIKey
- RATSWNOMCHFQGJ-XODSYJLDSA-N
- SMILES
- C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 |&1:8,22,r|
- CAS DataBase Reference
- 183814-30-4
Safety
- RIDADR
- UN 2811 6.1 / PGII
- WGK Germany
- 3
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H332Harmful if inhaled
H370Causes damage to organs
H373May cause damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
N-Bromosuccinimide Price
- Product number
- F9552
- Product name
- Formoterol fumarate dihydrate
- Purity
- >98% (HPLC)
- Packaging
- 10mg
- Price
- $221
- Updated
- 2024/03/01
- Product number
- PHR2703
- Product name
- Formoterol fumarate
- Purity
- PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer
- Packaging
- 500MG
- Price
- $400
- Updated
- 2024/03/01
- Product number
- F0372000
- Product name
- Formoterol fumarate dihydrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 10mg
- Price
- $181
- Updated
- 2022/05/15
- Product number
- F9552
- Product name
- Formoterol fumarate dihydrate
- Purity
- >98% (HPLC)
- Packaging
- 50mg
- Price
- $761
- Updated
- 2024/03/01
- Product number
- F0372000
- Product name
- Formoterol fumarate dihydrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- f0372000
- Price
- $153
- Updated
- 2024/03/01
Formoterol fumarate dihydrate Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
Formoterol is a selective β2-adrenergic receptor agonist. Formoterol is used as an antiasthmatic.
Uses
ForMoterol FuMarate Dihydrate is a selective β2-adrenergic receptor agonist,it is used as an antiasthmatic.
Biological Activity
Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.
Biochem/physiol Actions
β2-Adrenoreceptor agonist.
Drug interactions
The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].
References
[1] Aagaard, Lise . "A worldwide yearly survey of new data in adverse drug reactions." (2014).
Formoterol fumarate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Formoterol fumarate dihydrate Suppliers
- Tel
- +8615621883869 15621883869
- liutf@jewim.com.cn
- Country
- China
- ProdList
- 108
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 027-59207852 13308628970
- Fax
- QQ3130921841
- buy@fortunachem.com
- Country
- China
- ProdList
- 2871
- Advantage
- 58
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 86 592 2680277
- Fax
- 0086 592 2680237
- sale@simagchem.com
- Country
- China
- ProdList
- 430
- Advantage
- 55
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
View Lastest Price from Formoterol fumarate dihydrate manufacturers
- Product
- Formoterol Fumarate Monohydrate/ dihydrate 183814-30-4
- Price
- US $0.00/g/Bag
- Min. Order
- 10g
- Purity
- 98.5%min; JP14
- Supply Ability
- 20kg/month
- Release date
- 2021-06-03
- Product
- Formoterol Fumarate Dihydrate 183814-30-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 TONS
- Release date
- 2022-11-07
- Product
- (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate 183814-30-4
- Price
- US $65.00-650.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-20