ChemicalBook > CAS DataBase List > 7-METHYLINDOLE-3-CARBOXALDEHYDE

7-METHYLINDOLE-3-CARBOXALDEHYDE

Product Name
7-METHYLINDOLE-3-CARBOXALDEHYDE
CAS No.
4771-50-0
Chemical Name
7-METHYLINDOLE-3-CARBOXALDEHYDE
Synonyms
Antifungal agent 98;CCR1/5/8 activator 1;3-FORMYL-7-METHYLINDOLE;7-METHYLINDOLE-3-ALDEHYDE;7-Methyl-3-carboxaldehyde;7-METHYLINDOLE-3-CARBOXALDEHYDE;7-Methyl-3-indolecarboxaldehyde;7-METHYLINDOLE-3-CARBOXYALDEHYDE;7-METHYL-1H-INDOLE-3-CARBALDEHYDE;7-Methylindole-3-carboxaldehyde 98%
CBNumber
CB0229603
Molecular Formula
C10H9NO
Formula Weight
159.18
MOL File
4771-50-0.mol
More
Less

7-METHYLINDOLE-3-CARBOXALDEHYDE Property

Melting point:
206-208°C
Boiling point:
341.0±22.0 °C(Predicted)
Density 
1.226±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
Solid
pka
15.80±0.30(Predicted)
color 
Yellow to brown
Sensitive 
Air Sensitive
BRN 
122340
InChI
InChI=1S/C10H9NO/c1-7-3-2-4-9-8(6-12)5-11-10(7)9/h2-6,11H,1H3
InChIKey
KTUFZHVVJBHGKZ-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2C)C(C=O)=C1
CAS DataBase Reference
4771-50-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
M313628
Product name
7-Methylindole-3-carboxyaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
069433
Product name
3-Formyl-7-methylindole
Purity
96%
Packaging
1g
Price
$72
Updated
2021/12/16
Matrix Scientific
Product number
069433
Product name
3-Formyl-7-methylindole
Purity
96%
Packaging
500mg
Price
$57
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1555378
Product name
7-METHYLINDOLE-3-CARBOXALDEHYDE
Purity
95.00%
Packaging
250MG
Price
$120.82
Updated
2021/12/16
SynQuest Laboratories
Product number
4H15-1-55
Product name
7-Methylindole-3-carboxaldehyde
Purity
98%
Packaging
1g
Price
$176
Updated
2021/12/16
More
Less

7-METHYLINDOLE-3-CARBOXALDEHYDE Chemical Properties,Usage,Production

Uses

Reactant for preparation of:• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• ;Antibacterial and antituberculosis agents2• ;Antiandrogens effective against androgen receptor mutants3• ;Anti-bovine viral diarrhea virus (BVDV) agents4• ;Receptor subtype 5 antagonists5• ;Glucocorticoid receptor ligands6• ;Necroptosis inhibitors7• ;Orally efficacious small-molecule sctivator of the insulin receptor8

Uses

Reactant for preparation of:

  • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Antibacterial and antituberculosis agents
  • Antiandrogens effective against androgen receptor mutants
  • Anti-bovine viral diarrhea virus (BVDV) agents
  • Receptor subtype 5 antagonists
  • Glucocorticoid receptor ligands
  • Necroptosis inhibitors
  • Orally efficacious small-molecule sctivator of the insulin receptor

Synthesis

933-67-5

100-97-0

4771-50-0

General procedure for the synthesis of 7-methylindole-3-carboxaldehyde from 7-methylindole and ouvertropine: To a 50 mL round-bottomed flask fitted with a magnetic stirrer were added sequentially 7-methylindole (1.0 mmol, 1.0 eq.), hexamethylenetetetramine (HMTA, 2.0 mmol, 0.2803 g, 2.0 eq.), activated carbon (0.1 g), and N,N- dimethylformamide (DMF, 2 mL). Iodine (I2, 0.2 mmol, 0.0507 g, 20 mol%) was then added and the flask was assembled with a reflux condenser tube. The reaction mixture was stirred at 120 °C and the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was cooled to room temperature. The resulting mixture was filtered through a diatomaceous earth pad and the filter cake was washed well with ethyl acetate (EtOAc, 4 x 6 mL). The combined filtrates were washed sequentially with 0.5 M aqueous hydrochloric acid (10 mL), saturated sodium bicarbonate (NaHCO3) solution (10 mL), and saturated sodium chloride (NaCl) solution (10 mL), dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel fast column chromatography, and the target product 7-methylindole-3-carbaldehyde was obtained by using a mixed solvent of hexane and ethyl acetate as eluent.

References

[1] Tetrahedron Letters, 2017, vol. 58, # 30, p. 2877 - 2880
[2] Patent: CN108329249, 2018, A. Location in patent: Paragraph 0041-0044; 0066-0069

7-METHYLINDOLE-3-CARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

7-METHYLINDOLE-3-CARBOXALDEHYDE Suppliers

China 123 Europe 2 Germany 5 India 2 Switzerland 3 United Kingdom 10 United States 26 Global 171
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynChem，Inc
Tel
--
Fax
--
Email
sales@synchem.com
Country
United States
ProdList
4697
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Sphinx Scientific Laboratory, LLC
Tel
--
Fax
--
Email
sales@sphinxscientificlab.com
Country
United States
ProdList
3343
Advantage
50
W & J PharmaChem, Inc.
Tel
--
Fax
--
Email
info@wjpharmachem.com
Country
United States
ProdList
595
Advantage
50
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
AQS-USA.INC.
Tel
--
Fax
--
Country
United States
ProdList
893
Advantage
30
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Synthonix
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
1423
Advantage
68
Synchem Inc.
Tel
--
Fax
--
Email
catalog@synchem.com
Country
United States
ProdList
1154
Advantage
46
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
More
Less

View Lastest Price from 7-METHYLINDOLE-3-CARBOXALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
7-Methyl-1H-indole-3-carbaldehyde 4771-50-0
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
7-Methylindole-3-carboxaldehyde 4771-50-0
Price
US $1.00-1.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2024-07-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
7-METHYLINDOLE-3-CARBOXALDEHYDE 4771-50-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

4771-50-0, 7-METHYLINDOLE-3-CARBOXALDEHYDERelated Search:

5-METHOXY-1-METHYLINDOLE-3-CARBOXALDEHYDE 7-METHYLINDOLE-3-CARBOXALDEHYDE Methyl3-formyl-1H-indole-7-carboxylate 1-METHYLINDOLE-3-CARBOXALDEHYDE 5-METHYLINDOLE-3-CARBOXALDEHYDE 2-METHYLINDOLE-3-CARBOXALDEHYDE 6-METHYLINDOLE-3-CARBOXALDEHYDE 7-Methylindole IFLAB-BB F2113-0047 7-ETHYLINDOLE-3-GLYOXYLIC ACID ETHYL ESTER CILANSETRON 2-TERT-BUTYL-4-CHLORO-7-METHYL-1H-INDOLE-3-CARBALDEHYDE 3-FORMYL-1H-INDOLE-7-CARBOXYLIC ACID CHEMBRDG-BB 6404048 7-ETHYL-1H-INDOLE-3-CARBALDEHYDE 6-METHOXY-1-METHYLINDOLE-3-CARBOXALDEHYDE 4-METHYLINDOLE-3-CARBOXALDEHYDE 1-METHYLINDOLE-2-CARBOXALDEHYDE 97

  • 7-METHYLINDOLE7-METHYLINDOLE-3-CARBOXALDEHYDE
  • 7-Methylindole-3-carboxaldehyde in stock Factory
  • 7-METHYL-1H-INDOLE-3-CARBALDEHYDE
  • 7-METHYLINDOLE-3-ALDEHYDE
  • 7-METHYLINDOLE-3-CARBOXALDEHYDE
  • 7-METHYLINDOLE-3-CARBOXYALDEHYDE
  • 3-FORMYL-7-METHYLINDOLE
  • 1H-Indole-3-carboxaldehyde, 7-methyl- (9CI)
  • 7-Methylindole-3-carboxaldehyde 98%
  • 7-Methyl-3-indolecarboxaldehyde
  • 7-METHYLINDOLE-3-CARBOXALDEHYDE 98% (HPLC)
  • 7-Methyl-1H-indole-3-carboxaldehyde
  • 7-METHYLINDOLE-3-CARBOXALDEHYDE(7MeIAld)
  • 7-Methyl-3-carboxaldehyde
  • 1H-Indole-3-carboxaldehyde, 7-methyl-
  • CCR1/5/8 activator 1
  • Antifungal agent 98
  • 4771-50-0
  • ALDEHYDE
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • C10-C12
  • Aldehydes
  • Building Blocks
  • C10
  • Carbonyl Compounds
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Organic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • ALDEHYDE
  • Indoles and derivatives
  • Indole
  • Heterocyclic Compounds