Pamoic acid disodium salt
- Product Name
- Pamoic acid disodium salt
- CAS No.
- 6640-22-8
- Chemical Name
- Pamoic acid disodium salt
- Synonyms
- PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
- CBNumber
- CB0247382
- Molecular Formula
- C23H17NaO6
- Formula Weight
- 412.37
- MOL File
- 6640-22-8.mol
Pamoic acid disodium salt Property
- Melting point:
- 300 °C
- Density
- 1.55[at 20℃]
- vapor pressure
- 0.001Pa at 25℃
- storage temp.
- Desiccate at RT
- solubility
- insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO
- form
- solid
- color
- Pale yellow
- Water Solubility
- 43g/L at 20℃
- LogP
- -3.2 at 20℃
- CAS DataBase Reference
- 6640-22-8(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-37/38-41-48
- Safety Statements
- 24/25-45-36/37/39-26-22
- WGK Germany
- 3
- HS Code
- 2918.29.7500
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P5022
- Product name
- Pamoic acid disodium salt
- Packaging
- 25g
- Price
- $101
- Updated
- 2024/03/01
- Product number
- P1059
- Product name
- Pamoic Acid Disodium Salt Monohydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $61
- Updated
- 2024/03/01
- Product number
- P1059
- Product name
- Pamoic Acid Disodium Salt Monohydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 250g
- Price
- $295
- Updated
- 2024/03/01
- Product number
- 4298
- Product name
- Pamoic acid disodium salt
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $101
- Updated
- 2021/12/16
- Product number
- P173503
- Product name
- Pamoic acid disodium salt
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
Pamoic acid disodium salt Chemical Properties,Usage,Production
Chemical Properties
pale yellow to yellow powder
Uses
Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.
Flammability and Explosibility
Not classified
Biological Activity
Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.
Pamoic acid disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pamoic acid disodium salt manufacturers
- Product
- 4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- Pamoic Acid Disodium Salt Monohydrate 6640-22-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500KG
- Release date
- 2018-08-19