Calcium aspirin
- Product Name
- Calcium aspirin
- CAS No.
- 69-46-5
- Chemical Name
- Calcium aspirin
- Synonyms
- Ascal;Dispril;Disprin;Solaspin;Kalsetal;calcium aspirin;Aspirin calcium;Aspirin, calcium salt;CALCIUM ACETYLSALICYLATE;calcium 2-acetoxybenzoate
- CBNumber
- CB0253514
- Molecular Formula
- C18H14CaO8
- Formula Weight
- 398.38
- MOL File
- 69-46-5.mol
N-Bromosuccinimide Price
- Product number
- API0013513
- Product name
- CALCIUM ASPIRIN
- Purity
- 95.00%
- Packaging
- 100KG
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 100mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 250mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 500mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 1g
- Price
- $634
- Updated
- 2021/12/16
Calcium aspirin Chemical Properties,Usage,Production
Uses
Aspirin calcium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin calcium induces apoptosis. Aspirin calcium inhibits the activation of NF-κB. Aspirin calcium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[1][2][3][4][5][6].
References
[1] Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and induciblecyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7. DOI:10.1073/pnas.90.24.11693
[2] Blanco FJ, et al. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. J Rheumatol. 1999 Jun;26(6):1366-73. PMID:10381057
[3] Wu KK, et al. Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. DOI:10.1055/s-2003-40668
[4] Kopp E, et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. DOI:10.1126/science.8052854
[5] Burch JW, et al. Inhibition of platelet prostaglandin synthetase by oral aspirin. J Clin Invest. 1978 Feb;61(2):314-9. DOI:10.1172/JCI108941
[6] Elwood PC, et al. Aspirin, salicylates, and cancer. Lancet. 2009 Apr 11;373(9671):1301-9. DOI:10.1016/S0140-6736(09)60243-9
[7] Loux JJ, DePalma PD, Yankell SL. Antipyretic testing of aspirin in rats. Toxicol Appl Pharmacol. 1972 Aug;22(4):672-5. DOI:10.1016/0041-008x(72)90295-5
[8] Yomna I Mahmoud, et al. Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation. Biomed Pharmacother. 2019. DOI:10.1016/j.biopha.2018.10.118
[9] Zhongzhi Wang, et al. Protective Effects of Ginger against Aspirin-Induced Gastric Ulcers in Rats. Yonago Acta Med. 2011, 54, 1.
Calcium aspirin Preparation Products And Raw materials
Raw materials
Preparation Products
Calcium aspirin Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from Calcium aspirin manufacturers
- Product
- Calcium aspirin 69-46-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10tons
- Release date
- 2020-02-18