Calcium aspirin
- Product Name
- Calcium aspirin
- CAS No.
- 69-46-5
- Chemical Name
- Calcium aspirin
- Synonyms
- Ascal;Dispril;Disprin;Solaspin;Kalsetal;calcium aspirin;Aspirin calcium;Aspirin, calcium salt;CALCIUM ACETYLSALICYLATE;calcium 2-acetoxybenzoate
- CBNumber
- CB0253514
- Molecular Formula
- C18H14CaO8
- Formula Weight
- 398.38
- MOL File
- 69-46-5.mol
N-Bromosuccinimide Price
- Product number
- API0013513
- Product name
- CALCIUM ASPIRIN
- Purity
- 95.00%
- Packaging
- 100KG
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 100mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 250mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 500mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- FC150092
- Product name
- Calciumacetylsalicylate
- Packaging
- 1g
- Price
- $634
- Updated
- 2021/12/16
Calcium aspirin Chemical Properties,Usage,Production
Uses
Aspirin calcium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin calcium induces apoptosis. Aspirin calcium inhibits the activation of NF-κB. Aspirin calcium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[1][2][3][4][5][6].
References
[1] Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and induciblecyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7. DOI:10.1073/pnas.90.24.11693
[2] Blanco FJ, et al. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. J Rheumatol. 1999 Jun;26(6):1366-73. PMID:10381057
[3] Wu KK, et al. Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. DOI:10.1055/s-2003-40668
[4] Kopp E, et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. DOI:10.1126/science.8052854
[5] Burch JW, et al. Inhibition of platelet prostaglandin synthetase by oral aspirin. J Clin Invest. 1978 Feb;61(2):314-9. DOI:10.1172/JCI108941
[6] Elwood PC, et al. Aspirin, salicylates, and cancer. Lancet. 2009 Apr 11;373(9671):1301-9. DOI:10.1016/S0140-6736(09)60243-9
[7] Loux JJ, DePalma PD, Yankell SL. Antipyretic testing of aspirin in rats. Toxicol Appl Pharmacol. 1972 Aug;22(4):672-5. DOI:10.1016/0041-008x(72)90295-5
[8] Yomna I Mahmoud, et al. Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation. Biomed Pharmacother. 2019. DOI:10.1016/j.biopha.2018.10.118
[9] Zhongzhi Wang, et al. Protective Effects of Ginger against Aspirin-Induced Gastric Ulcers in Rats. Yonago Acta Med. 2011, 54, 1.
Calcium aspirin Preparation Products And Raw materials
Raw materials
Preparation Products
Calcium aspirin Suppliers
View Lastest Price from Calcium aspirin manufacturers
- Product
- Calcium aspirin 69-46-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10tons
- Release date
- 2020-02-18