ChemicalBook > CAS DataBase List > N3-PEG6-tBu

N3-PEG6-tBu

Product Name: N3-PEG6-tBu
CAS No.: 406213-76-1
Chemical Name: N3-PEG6-tBu
Synonyms: N3-PEG6-tBu;Azido-PEG6-C2-Boc;Azido-PEG6-COOtBu;Azido-PEG6-tBu Ester;N3-PEG6-CH2CH2COOtBu;Azido-PEG6-CH2CH2COOtBu;Azido-PEG7-t-butyl ester;Azido-PEG7-t-butly ester;N3-PEG6-CH2CH2COO^{t<;tert-butyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate}
CBNumber: CB02546988
Molecular Formula: C19H37N3O8
Formula Weight: 435.51238
MOL File: 406213-76-1.mol

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N3-PEG6-tBu Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C19H37N3O8/c1-19(2,3)30-18(23)4-6-24-8-10-26-12-14-28-16-17-29-15-13-27-11-9-25-7-5-21-22-20/h4-17H2,1-3H3
InChIKey: HRNUWAOLFSWRDG-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS103950
Product name: N3-PEG6-CH2CH2COOtBu
Purity: 95+%
Packaging: 250mg
Price: $322
Updated: 2021/12/16

BroadPharm

Product number: BP-20507
Product name: Azido-PEG6-t-butylester
Purity: 98%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

ChemPep

Product number: 280703
Product name: N3-PEG6-tBu
Packaging: 1g
Price: $610
Updated: 2021/12/16

Activate Scientific

Product number: AS103950
Product name: N3-PEG6-CH2CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $634
Updated: 2021/12/16

ChemPep

Product number: 280703
Product name: N3-PEG6-tBu
Packaging: 5g
Price: $1583
Updated: 2021/12/16

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N3-PEG6-tBu Chemical Properties,Usage,Production

Description

Azido-PEG6-t-butyl ester is a PEG molecule consisting of an azide group and a t-butyl ester moiety. he azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG5 spacer increases solubility in aqueous media.

Uses

Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG6-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N3-PEG6-tBu manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG6-t-Butyl ester 406213-76-1
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

406213-76-1, N3-PEG6-tBuRelated Search:

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N3-PEG6-tBu

N3-PEG6-CH2CH2COOtBu

21-Azido-4,7,10,13,16,19-hexaoxaheneicosanoic acid 1,1-dimethylethyl ester

Azido-PEG7-t-butly ester

Azido-PEG7-t-butyl ester

N3-PEG6-CH2CH2COOtBu

Azido-PEG6-COOtBu

Azido-PEG6-C2-Boc

tert-butyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate

Azido-PEG6-tBu Ester

N3-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-azido-, 1,1-dimethylethyl ester

Azido-PEG6-CH2CH2COOtBu

N3-PEG6-CH2CH2COOt<

406213-76-1

C19H37N3O8

peg