ChemicalBook > CAS DataBase List > POLYOXIN D

POLYOXIN D

Product Name
POLYOXIN D
CAS No.
22976-86-9
Chemical Name
POLYOXIN D
Synonyms
polyoxinz;polyoxorim;POLYOXIN D;POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS;Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE;2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester);1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid;β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-
CBNumber
CB0265177
Molecular Formula
C17H23N5O14
Formula Weight
521.39
MOL File
22976-86-9.mol
More
Less

POLYOXIN D Property

Melting point:
173-175 °C (decomp)
Density 
1.864±0.06 g/cm3(Predicted)
pka
2.67±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
P688083
Product name
PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE
Packaging
2.5mg
Price
$500
Updated
2021/12/16
TRC
Product number
P688083
Product name
PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE
Packaging
10mg
Price
$1865
Updated
2021/12/16
More
Less

POLYOXIN D Chemical Properties,Usage,Production

Uses

Polyoxin D,?Streptomyces cacaoi var. asoensis is a specific inhibitor of fungal chitin synthetase.

Definition

ChEBI: A member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks.

Enzyme inhibitor

This pyrimidin nucleoside analogue and antifungal antibiotic (FWfree-acid = 521.39 g/mol; CAS 22976-86-9; 33401-46-6 for the zinc salt), produced by soil organisms Streptomyces cacaoi and S. piomogenus, inhibits chitin biosynthesis, Ki = 6 μM, thereby blocking septum formation. The zinc salt of polyyoxin is used to control Rice Sheath Blight, caused by the fungus Rhizoctonia solani, as well as the turfgrass disease Brown Patch, caused by other Rhizoctonia species. Polyoxin D also inhibits Neurospora crassa, but is nontoxic to land mammals, insects, or birds, when applied to plants as the wettable powder form known as Endorse?. Target(s): chitin synthase (1- 24); chitin synthase B; chitin synthase, canChs1A; WdChs4p, a chitin synthase 3 homologue.

POLYOXIN D Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

POLYOXIN D Suppliers

China 14 India 1 South Korea 1 United Kingdom 1 United States 8 Global 25
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82

22976-86-9, POLYOXIN DRelated Search:

COBALT(II) ACETYLACETONATE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Benzyl isocyanide Tosylmethyl isocyanide PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) Ethyl isocyanoacetate Cupric acetylacetonate Aluminum acetylacetonate METHYL ISOCYANOACETATE TERT-BUTYL ISOCYANIDE SALCOMINE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) POLYOXIN A

  • POLYOXIN D
  • POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS
  • 1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci
  • 2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester)
  • polyoxinz
  • polyoxorim
  • 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid
  • 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
  • β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-
  • Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE
  • 22976-86-9
  • C17H23N5O14