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POLYOXIN D

Product Name
POLYOXIN D
CAS No.
22976-86-9
Chemical Name
POLYOXIN D
Synonyms
polyoxinz;polyoxorim;POLYOXIN D;POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS;Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE;2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester);1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid;β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-
CBNumber
CB0265177
Molecular Formula
C17H23N5O14
Formula Weight
521.39
MOL File
22976-86-9.mol
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POLYOXIN D Property

Melting point:
173-175 °C (decomp)
Density 
1.864±0.06 g/cm3(Predicted)
pka
2.67±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P688083
Product name
PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE
Packaging
2.5mg
Price
$500
Updated
2021/12/16
TRC
Product number
P688083
Product name
PolyoxinD, Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE
Packaging
10mg
Price
$1865
Updated
2021/12/16
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POLYOXIN D Chemical Properties,Usage,Production

Uses

Polyoxin D,?Streptomyces cacaoi var. asoensis is a specific inhibitor of fungal chitin synthetase.

Definition

ChEBI: A member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks.

Enzyme inhibitor

This pyrimidin nucleoside analogue and antifungal antibiotic (FWfree-acid = 521.39 g/mol; CAS 22976-86-9; 33401-46-6 for the zinc salt), produced by soil organisms Streptomyces cacaoi and S. piomogenus, inhibits chitin biosynthesis, Ki = 6 μM, thereby blocking septum formation. The zinc salt of polyyoxin is used to control Rice Sheath Blight, caused by the fungus Rhizoctonia solani, as well as the turfgrass disease Brown Patch, caused by other Rhizoctonia species. Polyoxin D also inhibits Neurospora crassa, but is nontoxic to land mammals, insects, or birds, when applied to plants as the wettable powder form known as Endorse?. Target(s): chitin synthase (1- 24); chitin synthase B; chitin synthase, canChs1A; WdChs4p, a chitin synthase 3 homologue.

POLYOXIN D Preparation Products And Raw materials

Raw materials

Preparation Products

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POLYOXIN D Suppliers

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22976-86-9, POLYOXIN DRelated Search:


  • POLYOXIN D
  • POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS
  • 1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci
  • 2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester)
  • polyoxinz
  • polyoxorim
  • 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid
  • 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
  • β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-
  • Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE
  • 22976-86-9
  • C17H23N5O14