ChemicalBook > CAS DataBase List > 10-Nitrocamptothecin
10-Nitrocamptothecin
- Product Name
- 10-Nitrocamptothecin
- CAS No.
- 86639-62-5
- Chemical Name
- 10-Nitrocamptothecin
- Synonyms
- RUBETICAN;9-NITRO-CPT;9-Nitro-20(S)-camptothecine;CAMPTOTHECIN, 9-NITRO-20(S)-;10-Nitrocamptothecin ISO 9001:2015 REACH;4α-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-di;(S)-4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-nitro-, (4S)-
- CBNumber
- CB0270140
- Molecular Formula
- C20H15N3O6
- Formula Weight
- 393.35
- MOL File
- 86639-62-5.mol
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10-Nitrocamptothecin Property
- Boiling point:
- 827.4±65.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- pka
- 11.17±0.20(Predicted)
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N-Bromosuccinimide Price
Matrix Scientific
- Product number
- 099302
- Product name
- (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $742
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 099302
- Product name
- (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1647
- Updated
- 2021/12/16
AK Scientific
- Product number
- 9741AF
- Product name
- (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- Packaging
- 1g
- Price
- $2273
- Updated
- 2021/12/16
Crysdot
- Product number
- CD32000239
- Product name
- 9-Nitrocamptothecin
- Purity
- 95+%
- Packaging
- 25mg
- Price
- $170
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DCX-058
- Product name
- 9-Nitrocamptothecin
- Purity
- >98%,StandardReferencesGrade
- Packaging
- 20mg
- Price
- $280
- Updated
- 2021/12/16
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10-Nitrocamptothecin Chemical Properties,Usage,Production
Uses
Whether cells can divide depends on the two key points of entering S phase and M phase. Studies have found that 10-Nitrocamptothecin can induce apoptosis. After administration, both S phase and G2M phase of cell growth are delayed. Inhibition occurred throughout the cell cycle and was found to be dose- and time-dependent.
Definition
ChEBI: Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone.
10-Nitrocamptothecin Preparation Products And Raw materials
Raw materials
Preparation Products
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10-Nitrocamptothecin Suppliers
- Tel
- --
- Fax
- --
- sales@matrixscientific.com
- Country
- United States
- ProdList
- 6632
- Advantage
- 80
- Tel
- --
- Fax
- --
- info@rintechinc.com
- Country
- United States
- ProdList
- 3416
- Advantage
- 60
- Tel
- --
- Fax
- --
- sales@waterstonetech.com
- Country
- United States
- ProdList
- 6786
- Advantage
- 30
- Tel
- --
- Fax
- --
- sales@2apharmachem.com
- Country
- United States
- ProdList
- 6137
- Advantage
- 39
- Tel
- --
- Fax
- --
- sales@3bsc.com
- Country
- United States
- ProdList
- 6718
- Advantage
- 47
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View Lastest Price from 10-Nitrocamptothecin manufacturers
Career Henan Chemical Co
- Product
- 9-Nitrocamptothecin 86639-62-5
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1kg; 50kg; 500kg
- Release date
- 2019-12-24
86639-62-5, 10-NitrocamptothecinRelated Search:
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(+)-Camptothecin
4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Camptothecin Series--10-hydroxycamptothecin
Hydroxyl camptothecine
7-Ethyl camptothecin
10-HYDROXY-9-NITROCAMPTOTHECIN
Rubitecan
10-Nitrocamptothecin
12-nitrocamptothecin