ChemicalBook > CAS DataBase List > 2-Chlorocinnamic acid

2-Chlorocinnamic acid

Product Name
2-Chlorocinnamic acid
CAS No.
3752-25-8
Chemical Name
2-Chlorocinnamic acid
Synonyms
AKOS BBB/195;AKOS B004073;AKOS BBS-00006452;Chlorocinnamicacid;RARECHEM BK HC T319;2-Chlorocinnamicaci;o-chloro-cinnamicaci;2-CLOROCINNAMIC ACID;O-CHLOROCINNAMIC ACID;OTAVA-BB BB0125160239
CBNumber
CB0278409
Molecular Formula
C9H7ClO2
Formula Weight
182.6
MOL File
3752-25-8.mol
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2-Chlorocinnamic acid Property

Melting point:
208-210 °C(lit.)
Boiling point:
260.71°C (rough estimate)
Density 
1.2377 (rough estimate)
refractive index 
1.5426 (estimate)
storage temp. 
Room temperature.
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Water Solubility 
Insoluble in water
form 
powder to crystal
pka
4.23(at 25℃)
color 
White to Almost white
BRN 
1365198
InChIKey
KJRRTHHNKJBVBO-AATRIKPKSA-N
CAS DataBase Reference
3752-25-8(CAS DataBase Reference)
NIST Chemistry Reference
2-Chlorocinnamic acid(3752-25-8)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-22
Safety Statements 
36-26-36/37
WGK Germany 
3
RTECS 
GD8450000
Hazard Note 
Irritant
HS Code 
29124990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
C0974
Product name
2-Chlorocinnamic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$36
Updated
2024/03/01
Alfa Aesar
Product number
L01606
Product name
2-Chlorocinnamic acid, predominantly trans, 99%
Packaging
25g
Price
$38.3
Updated
2021/12/16
Alfa Aesar
Product number
L01606
Product name
2-Chlorocinnamic acid, predominantly trans, 99%
Packaging
100g
Price
$100
Updated
2021/12/16
TRC
Product number
C428250
Product name
(E)-3-(2-Chlorophenyl)acrylicacid
Packaging
2.5g
Price
$65
Updated
2021/12/16
TRC
Product number
C428250
Product name
(E)-3-(2-Chlorophenyl)acrylicacid
Packaging
500mg
Price
$45
Updated
2021/12/16
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2-Chlorocinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder. Insoluble in water, soluble in ethanol, ethyl acetate and other organic solvents.

Uses

2-Chlorocinnamic acid is a kind of trans-cinnamate. It is used in organic synthesis.

Biological Functions

2-Chlorocinnamic acid is a cinnamic acid derivative that inhibits the hydroxylation of phenylpropanoids. It has been shown to inhibit the activity of cinnamic acid derivatives and their hydroxylation in cell lines, which is linked to the inhibition of cellulose acetate synthesis. 2-Chlorocinnamic acid also has an inhibitory effect on the chloride ion and water molecule. The chloride ion may be needed for the formation of hydrochloric acid, which is necessary for cellulose acetate hydrolysis, while water molecules are involved in many biochemical reactions. 2-Chlorocinnamic acid affects human cell lines at temperatures between 10°C and 37°C and at regiospecific sites. This oxidative dehalogenation reaction catalyzed by R. rubra was found to be regiospecific for 2-chlorocinnamic acid; the chloride ion was probably removed after the ring fission reaction.

Synthesis

O-chlorocinnamic acid is prepared by reacting o-phthalaldehyde with malonic acid.

2-Chlorocinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chlorocinnamic acid Suppliers

Wuhan lenmaike Industrial Co., Ltd.
Tel
027-027-83916065 18062522895
Fax
027-83916065
Email
landmarkorganic@qq.com
Country
China
ProdList
68
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3989
Advantage
58
Zaoyang Cixiang Pharmaceutical Technology Co., LTD
Tel
15671321689
Email
carrie@cixiangyy.com
Country
China
ProdList
21
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
969
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
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View Lastest Price from 2-Chlorocinnamic acid manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Chlorocinnamic Acid 3752-25-8
Price
US $19.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
50 ton
Release date
2024-08-23
Hebei Fengjia New Material Co., Ltd
Product
2-Chlorocinnamic acid 3752-25-8
Price
US $7.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-09-06
Hebei Kingfiner Technology Development Co.Ltd
Product
2-Chlorocinnamic acid 3752-25-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000kg
Release date
2024-05-08

3752-25-8, 2-Chlorocinnamic acidRelated Search:


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