ChemicalBook > CAS DataBase List > Bromo-PEG2-t-butyl ester

Bromo-PEG2-t-butyl ester

Product Name: Bromo-PEG2-t-butyl ester
CAS No.: 1381861-91-1
Chemical Name: Bromo-PEG2-t-butyl ester
Synonyms: Br-PEG2-COOtBu;CAS_1381861-91-1;Bromo-PEG2-C2-Boc;Br-PEG2-CH2CH2COOtBu;Br-PEG2-t-butyl ester;Bromo-PEG3-t-butyl ester;Bromo-PEG2-t-butyl ester;Bromo-PEG2-tert-butyl Ester;tert-Butyl 3-(2-(2-bromoethoxy)ethoxy)propanoate;Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB03048715
Molecular Formula: C11H21BrO4
Formula Weight: 297.19
MOL File: 1381861-91-1.mol

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Bromo-PEG2-t-butyl ester Property

Boiling point:: 332.0±22.0 °C(Predicted)
Density: 1.240±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C11H21BrO4/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h4-9H2,1-3H3
InChIKey: UOYAYHGUAATLSG-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCBr

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B800375
Product name: Bromo-Peg2-T-ButylEster
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1348
Product name: Bromo-PEG2-t-butyl ester
Packaging: 250mg
Price: $546
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1349
Product name: Bromo-PEG3-t-butyl ester
Packaging: 250mg
Price: $546
Updated: 2021/12/16

BroadPharm

Product number: BP-20681
Product name: Bromo-PEG2-t-butylester
Purity: 98%
Packaging: 1g
Price: $750
Updated: 2021/12/16

BroadPharm

Product number: BP-20681
Product name: Bromo-PEG2-t-butylester
Purity: 98%
Packaging: 5G
Price: $1540
Updated: 2021/12/16

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Bromo-PEG2-t-butyl ester Chemical Properties,Usage,Production

Description

Bromo-PEG2-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG2-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Bromo-PEG2-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Br-PEG2-COOtBu 1381861-91-1
Price: US $0.00/g
Min. Order: 25g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-25

Career Henan Chemical Co

Product: Bromo-PEG2-t-butyl ester 1381861-91-1
Price: US $2.00/g
Min. Order: 1g
Purity: 95~99.9%
Supply Ability: 5KG
Release date: 2020-03-05

1381861-91-1, Bromo-PEG2-t-butyl esterRelated Search:

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CAS_1381861-91-1

Bromo-PEG2-C2-Boc

Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester

Br-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester

Bromo-PEG2-tert-butyl Ester

1381861-91-1

C11H21BrO4