ChemicalBook > CAS DataBase List > m-PEG2-acid

m-PEG2-acid

Product Name
m-PEG2-acid
CAS No.
149577-05-9
Chemical Name
m-PEG2-acid
Synonyms
mPEG1-COOH;mPEG2-COOH;m-PEG2-acid;m-dPEG2-acid;m-dPEG??-acid;mPEG1-CH2CH2COOH;Methyl-PEG2-acid;MeOCH2CH2OCH2COOH;m-dPEG??-acid (QBD-10326);3-(2-Methoxyethoxy)propionic Acid
CBNumber
CB03062562
Molecular Formula
C6H12O4
Formula Weight
148.16
MOL File
149577-05-9.mol
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m-PEG2-acid Property

Boiling point:
244.2±20.0 °C(Predicted)
Density 
1.098±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.28±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C6H12O4/c1-9-4-5-10-3-2-6(7)8/h2-5H2,1H3,(H,7,8)
InChIKey
KWMXBFIAGYXCCC-UHFFFAOYSA-N
SMILES
C(O)(=O)CCOCCOC
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
B421828
Product name
3-(2-methoxyethoxy)propanoicacid
Packaging
25mg
Price
$45
Updated
2021/12/16
TRC
Product number
B421828
Product name
3-(2-methoxyethoxy)propanoicacid
Packaging
50mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
X3859
Product name
M-PEG2-acid
Packaging
250mg
Price
$191
Updated
2021/12/16
dPEG
Product number
10326
Product name
m-dPEG®₂-acid
Packaging
1000mg
Price
$230
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG1630
Product name
MeO-EPr-COOH
Packaging
100mg
Price
$270
Updated
2021/12/16
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m-PEG2-acid Chemical Properties,Usage,Production

Description

m-PEG2-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Definition

ChEBI: 3-(2-methoxyethoxy)propanoic acid is a monocarboxylic acid that is propanoic acid substituted at C-3 by a 2-methoxyethoxy group. It has a role as a metabolite. It is a monocarboxylic acid and an ether.

IC 50

PEGs

References

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74

m-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG2-acid Suppliers

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View Lastest Price from m-PEG2-acid manufacturers

LAURENT
Product
mPEG1-CH2CH2COOH 149577-05-9
Price
US $448.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-13
Xian confluore Biological Technology Co., Ltd.
Product
m-PEG2-COOH 149577-05-9
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-27