ChemicalBook > CAS DataBase List > ML264

ML264

Product Name
ML264
CAS No.
1550008-55-3
Chemical Name
ML264
Synonyms
ML264;CS-2175;ML264(C);CID-51003603;ML-264 (ML264;ML264 >=98% (HPLC);ML264, 10 mM in DMSO;ML-264; ML264; ML 264; CID-51003603;ML-264,Inhibitor,Krüppel-like factor,ML 264,inhibit,ML264,KLF;(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acry
CBNumber
CB03122680
Molecular Formula
C17H21ClN2O4S
Formula Weight
384.88
MOL File
1550008-55-3.mol
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ML264 Property

Boiling point:
701.0±60.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:64.0(Max Conc. mg/mL);166.63(Max Conc. mM)
form 
A crystalline solid
pka
12.84±0.46(Predicted)
color 
White to off-white
CAS DataBase Reference
1550008-55-3
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18880
Product name
ML-264
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
18880
Product name
ML-264
Purity
≥98%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
18880
Product name
ML-264
Purity
≥98%
Packaging
10mg
Price
$169
Updated
2024/03/01
Cayman Chemical
Product number
18880
Product name
ML-264
Purity
≥98%
Packaging
25mg
Price
$305
Updated
2024/03/01
TRC
Product number
M425383
Product name
ML264
Packaging
5mg
Price
$185
Updated
2021/12/16
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ML264 Chemical Properties,Usage,Production

Uses

ML264 is a inhibitor of Krüppel-like Factor Five (KLF5).

in vivo

Single daily injections of ML264 at 10 mg/kg do not significantly affect tumor growth. However, twice daily injections of ML264 at 10 mg/kg or 25 mg/kg result in significant reductions in tumor growth, and this effect can be detected as early as two days after the first injection. The data also show that there is a concentration-dependent effect of ML264 on the tumor volume. Statistical analysis of tumor growth reveals significant tumor size reduction in mice treated twice daily with ML264 compared to those receiving only vehicle at day 5 and 10[2].

ML264 Preparation Products And Raw materials

Raw materials

Preparation Products

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1550008-55-3, ML264Related Search:


  • ML264
  • (2E)-3-(3-Chlorophenyl)-N-[2-[methyl(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-2-oxoethyl]-2-propenamide
  • CID-51003603
  • ML-264; ML264; ML 264; CID-51003603
  • CS-2175
  • 2-Propenamide, 3-(3-chlorophenyl)-N-[2-[methyl(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-2-oxoethyl]-, (2E)-
  • ML264 >=98% (HPLC)
  • (E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide
  • ML-264,Inhibitor,Krüppel-like factor,ML 264,inhibit,ML264,KLF
  • ML264(C)
  • ML264, 10 mM in DMSO
  • ML-264 (ML264
  • (E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acry
  • 1550008-55-3