PTP1B-IN-2

ChemicalBook > CAS DataBase List > PTP1B-IN-2

Product Name: PTP1B-IN-2
CAS No.: 1919853-46-5
Chemical Name: PTP1B-IN-2
Synonyms: MDK3465;PTP1B-IN-2;PTP1B inhibitor 2;PTP1B-IN-2, 10 mM in DMSO;PTP1B-IN-2;PTP1B INHIBITOR 2;Inhibitor,PTP-1B-IN-2,inhibit,PTP1BIN2,Phosphatase,PTP1B IN 2;Benzoic acid, 5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-, methyl ester
CBNumber: CB03309540
Molecular Formula: C34H36N2O9S2
Formula Weight: 680.79
MOL File: 1919853-46-5.mol

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PTP1B-IN-2 Property

Boiling point:: 813.4±75.0 °C(Predicted)
Density: 1.350±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: insol; PBS (pH 7.2): insol
form: A solid
pka: -3.81±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6881
Product name: PTP1B-IN-2
Purity: 99.85%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

Ambeed

Product number: A949653
Product name: PTP1B-IN-2
Purity: 98%
Packaging: 1mg
Price: $63
Updated: 2021/12/16

Crysdot

Product number: CD38000036
Product name: PTP1B-IN-2
Purity: 98%
Packaging: 1mg
Price: $105
Updated: 2021/12/16

Ambeed

Product number: A949653
Product name: PTP1B-IN-2
Purity: 98%
Packaging: 5mg
Price: $107
Updated: 2021/12/16

Ambeed

Product number: A949653
Product name: PTP1B-IN-2
Purity: 98%
Packaging: 10mg
Price: $139
Updated: 2021/12/16

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PTP1B-IN-2 Chemical Properties,Usage,Production

Biological Activity

PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B) with IC50 of 50 nM. It enhances insulin-mediated phosphorylation of insulin receptor beta (IRβ) and insulin-stimulated glucose uptake.

in vitro

PTP1B-IN-2 displays more than 40-fold selectivity for PTP1B over SHP-2 and LAR and 15-fold higher selectivity for PTP1B over the highly homologous TCPTP.

target

Target	Value
PTP1B (Cell-free assay)	50 nM

PTP1B-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PTP1B-IN-2 Suppliers

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1919853-46-5, PTP1B-IN-2Related Search:

ML346 5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one ML-228 ML188 (Racemate) ML 18 ML-098 ML277 ML 204 ML329 ML364 VU0456810 ML188 ML418 [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone ML213 N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine ML-327 ML264

PTP1B-IN-2

MDK3465

PTP1B inhibitor 2

PTP1B-IN-2;PTP1B INHIBITOR 2

Inhibitor,PTP-1B-IN-2,inhibit,PTP1BIN2,Phosphatase,PTP1B IN 2

Benzoic acid, 5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-, methyl ester

PTP1B-IN-2, 10 mM in DMSO

1919853-46-5