ChemicalBook > CAS DataBase List > 3-Hydroxy-3-methyl-2-butanone
3-Hydroxy-3-methyl-2-butanone
- Product Name
- 3-Hydroxy-3-methyl-2-butanone
- CAS No.
- 115-22-0
- Chemical Name
- 3-Hydroxy-3-methyl-2-butanone
- Synonyms
- Methylacetoin;3-Methylacetoin;3-HYDROXY-3-METHYL-2;Dimethylacetylcarbinol;ACETYLDIMETHYLCARBINOL;2-Methylbutan-2-ol-3-one;3-hydroxy-3-ethylbutanone;3-Hydroxy-3-methylbutanone;3-hydroxy-3-methyl-2-butanon;3-HYDROXY-3-METHYL-2-BUTANONE
- CBNumber
- CB0367448
- Molecular Formula
- C5H10O2
- Formula Weight
- 102.13
- MOL File
- 115-22-0.mol
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3-Hydroxy-3-methyl-2-butanone Property
- Melting point:
- 84-85 °C
- Boiling point:
- 140-141 °C (lit.)
- Density
- 0.971 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.415(lit.)
- Flash point:
- 108 °F
- storage temp.
- Flammables area
- solubility
- Soluble in chloroform.
- pka
- 13.28±0.29(Predicted)
- form
- Liquid
- color
- Clear colorless to yellow or light red
- BRN
- 1616385
- InChIKey
- BNDRWEVUODOUDW-UHFFFAOYSA-N
- LogP
- 0.112 (est)
- CAS DataBase Reference
- 115-22-0(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Butanone, 3-hydroxy-3-methyl- (115-22-0)
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Safety
- Risk Statements
- 10
- Safety Statements
- 23-24/25-22
- RIDADR
- UN 1224 3/PG 3
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29144000
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- H39604
- Product name
- 3-Hydroxy-3-methyl-2-butanone
- Purity
- 95% anhydrous basis
- Packaging
- 5g
- Price
- $49.4
- Updated
- 2023/01/07
Sigma-Aldrich
- Product number
- H39604
- Product name
- 3-Hydroxy-3-methyl-2-butanone
- Purity
- 95% anhydrous basis
- Packaging
- 25g
- Price
- $178
- Updated
- 2023/01/07
TCI Chemical
- Product number
- H0471
- Product name
- 3-Hydroxy-3-methyl-2-butanone
- Purity
- >95.0%(GC)
- Packaging
- 25mL
- Price
- $128
- Updated
- 2024/03/01
TCI Chemical
- Product number
- H0471
- Product name
- 3-Hydroxy-3-methyl-2-butanone
- Purity
- >95.0%(GC)
- Packaging
- 100mL
- Price
- $382
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- 043724
- Product name
- 3-Hydroxy-3-methyl-2-butanone, 90+%
- Packaging
- 5g
- Price
- $34.65
- Updated
- 2024/03/01
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3-Hydroxy-3-methyl-2-butanone Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
3-Hydroxy-3-methyl-2-butanone used to produce 2,5-dihydroxy-2-methyl-heptan-3-one, laboratory chemicals.
Application
3-Hydroxy-3-methyl-2-butanone is an alpha-hydroxy ketone compound. It can be used as a biologically active natural product and a pharmaceutical intermediate, and as a photoinitiator in UV-curable coatings. At the same time, α-hydroxyketone structural units are also widely used synthons in organic synthesis. Hydroxyl can be used as a mild reaction precursor for double bonds, ester groups, carbonyl groups, halogenated hydrocarbons and other groups. Carbonyl can be used as the reaction precursor of hydroxyl, amino, alkyl and other groups. Therefore, α-hydroxyketone compounds are a class of compounds with important application value.
Preparation
synthesis of 3-Hydroxy-3-methyl-2-butanone: 19ml of concentrated sulfuric acid (98wt%) was slowly mixed with 100ml of water, then 13g of yellow mercury oxide was added within 1.5h, 84g (1.0mol) of 2-methyl-3-butyn-2-ol was added dropwise to the sulfuric acid solution containing mercury oxide at 65-75°C, Then the reaction was stirred at 65-75°C for 30min, cooled to room temperature after the reaction was completed, the reaction product was subjected to suction filtration, the filtrate after suction filtration was extracted with ether (3×20ml), and the organic phase after extraction was water and hydrogen carbonate respectively. Washed with sodium solution, the washed organic phase was dried with anhydrous magnesium sulfate, and then filtered, the filtered filtrate was concentrated by rotary evaporation and then distilled, and the 140°C fraction was collected, 45.6 g of light yellow liquid was obtained as 3-hydroxy-3-methyl-2-butanone, and the yield was 32.2%.
Definition
ChEBI: 3-Hydroxy-3-methylbutan-2-one is a secondary alpha-hydroxy ketone.
3-Hydroxy-3-methyl-2-butanone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Hydroxy-3-methyl-2-butanone manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 3-HYDROXY-3-METHYL-2-BUTANONE 115-22-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
Career Henan Chemical Co
- Product
- 3-HYDROXY-3-METHYL-2-BUTANONE 115-22-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-23
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