Ropivacaine hydrochloride

Product Name: Ropivacaine hydrochloride
CAS No.: 132112-35-7
Chemical Name: Ropivacaine hydrochloride
Synonyms: ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
CBNumber: CB0369811
Molecular Formula: C17H26N2O.ClH.H2O
Formula Weight: 328.88
MOL File: 132112-35-7.mol

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Ropivacaine hydrochloride Property

Melting point:: 267-269°C
alpha: D20 -7.28° (c = 2 in water)
storage temp.: 2-8°C
solubility: H2O: soluble5mg/mL, clear
form: powder
color: white to off-white
optical activity: [α]/D -9 to -12, c = 1 in methanol
InChIKey: VSHFRHVKMYGBJL-CKUXDGONSA-N
CAS DataBase Reference: 132112-35-7(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi
Risk Statements: 26/27/28-41
Safety Statements: 22-36/37/39-45-39-26
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2933399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R0283
Product name: Ropivacaine hydrochloride monohydrate
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $84.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2303
Product name: Ropivacaine hydrochloride
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 500MG
Price: $253
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1605500
Product name: Ropivacaine hydrochloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Cayman Chemical

Product number: 21422
Product name: Ropivacaine (hydrochloride hydrate)
Purity: ≥98%
Packaging: 25mg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 21422
Product name: Ropivacaine (hydrochloride hydrate)
Purity: ≥98%
Packaging: 50mg
Price: $117
Updated: 2024/03/01

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Ropivacaine hydrochloride Chemical Properties,Usage,Production

Description

(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.

Chemical Properties

White Solid

Uses

Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.

Uses

Anesthetic (local).

Definition

ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.

General Description

Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Ropivacaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ropivacaine hydrochloride Suppliers

Canada 2 China 328 Europe 2 France 1 Germany 2 India 15 Italy 2 South Africa 1 South Korea 1 Switzerland 1 United Kingdom 8 United States 33 Global 396

Whyte Chemicals

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View Lastest Price from Ropivacaine hydrochloride manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Ropivacaine HCL 132112-35-7
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 99% HPLC
Supply Ability: 1000kg
Release date: 2024-11-23

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Ropivacaine hydrochloride 132112-35-7
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%-101%;EP
Supply Ability: 500KGS
Release date: 2021-06-17

Hebei Miaoyin Technology Co.,Ltd

Product: Ropivacaine hydrochloride 132112-35-7
Price: US $20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000
Release date: 2023-04-06

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132112-35-7

13112-35-7

CAS NO.98717-15

132115-35-7

C17H26N2OxHCL

C17H26N2OHCl

C17H26N2OHCLH2O

C17H28N2O2HCl

C17H26N2O2HClH2O

C17H26N2OClHH2O

Inhibitors

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals

API

132112-35-7