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Chloramphenicol sodium succinate

Product Name
Chloramphenicol sodium succinate
CAS No.
982-57-0
Chemical Name
Chloramphenicol sodium succinate
Synonyms
Nalecin;Mychel-S;Solnicol;Cloromoin;Nevimycin;Betamicetin;protophenicol;Clorofenicina;PubChem ID: 656580;Levomycetin-Nalcein
CBNumber
CB0406947
Molecular Formula
C15H15Cl2N2O8.Na
Formula Weight
445.19
MOL File
982-57-0.mol
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Chloramphenicol sodium succinate Property

Melting point:
>42oC (dec.)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
H2O: soluble50mg/mL
form 
solid
color 
White to Off-White
InChIKey
RPLOPBHEZLFENN-HTMVYDOJSA-M
CAS DataBase Reference
982-57-0(CAS DataBase Reference)
EPA Substance Registry System
Chloramphenicol sodium succinate (982-57-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36
WGK Germany 
3
RTECS 
AB6905000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C3787
Product name
Chloramphenicol succinate sodium salt
Purity
≥80% (HPLC)
Packaging
5g
Price
$73.7
Updated
2024/03/01
Sigma-Aldrich
Product number
C3787
Product name
Chloramphenicol succinate sodium salt
Purity
≥80% (HPLC)
Packaging
25g
Price
$295
Updated
2024/03/01
Sigma-Aldrich
Product number
C1425000
Product name
Chloramphenicol sodium succinate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
c1425000
Price
$90
Updated
2024/03/01
Sigma-Aldrich
Product number
C3787
Product name
Chloramphenicol succinate sodium salt
Purity
≥80% (HPLC)
Packaging
100g
Price
$730
Updated
2023/06/20
TRC
Product number
C325065
Product name
ChloramphenicolSuccinateSodium
Packaging
25g
Price
$140
Updated
2021/12/16
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Chloramphenicol sodium succinate Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white powder, hygroscopic

Uses

Chloramphenicol Succinate Sodium is a derivative of Chloramphenicol (C325030) which are broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.

Uses

Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weakly sodium hydroxide solutions. The sodium salt is the preferred formulation for pharmaceutical applications, providing a more readily soluble product. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

Uses

antibacterial, antirickettsial, inhibits protein synthesis

General Description

Chloramphenicol sodium succinate is the water-solublesodium salt of the hemisuccinate ester of chloramphenicol.Because of the low solubility of chloramphenicol, the sodiumsuccinate is preferred for intravenous administration. Theavailability of chloramphenicol from the ester followingintravenous administration is estimated to be 70% to 75%; theremainder is excreted unchanged. Poor availability ofthe active form from the ester following intramuscular injectionprecludes attaining effective plasma levels of the antibioticby this route. Orally administered chloramphenicol orits palmitate ester actually gives higher plasma levels of theactive antibiotic than does intravenously administered chloramphenicolsodium succinate. Nonetheless, effectiveconcentrations are achieved by either route.

General Description

White powder.

Air & Water Reactions

Freely soluble in water.

Fire Hazard

Flash point data for Chloramphenicol sodium succinate are not available, but Chloramphenicol sodium succinate is probably combustible.

Chloramphenicol sodium succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Chloramphenicol sodium succinate Suppliers

Chemopharma Gmbh
Tel
--
Fax
--
Email
office@chemopharma.com
Country
Austria
ProdList
325
Advantage
58
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View Lastest Price from Chloramphenicol sodium succinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Chloramphenicol sodium succinate 982-57-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2021-07-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
Chloramphenicol sodium succinate 982-57-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
Chloramphenicol sodium succinate 982-57-0
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2019-12-25

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