Chloramphenicol sodium succinate

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Chloramphenicol sodium succinate

Product Name: Chloramphenicol sodium succinate
CAS No.: 982-57-0
Chemical Name: Chloramphenicol sodium succinate
Synonyms: Nalecin;Mychel-S;Solnicol;Cloromoin;Nevimycin;Betamicetin;protophenicol;Clorofenicina;PubChem ID: 656580;Levomycetin-Nalcein
CBNumber: CB0406947
Molecular Formula: C15H15Cl2N2O8.Na
Formula Weight: 445.19
MOL File: 982-57-0.mol

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Chloramphenicol sodium succinate Property

Melting point:: >42oC (dec.)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: H2O: soluble50mg/mL
form: solid
color: White to Off-White
InChIKey: RPLOPBHEZLFENN-HTMVYDOJSA-M
CAS DataBase Reference: 982-57-0(CAS DataBase Reference)
EPA Substance Registry System: Chloramphenicol sodium succinate (982-57-0)

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Safety

Hazard Codes: Xn
Risk Statements: 40
Safety Statements: 22-36
WGK Germany: 3
RTECS: AB6905000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C3787
Product name: Chloramphenicol succinate sodium salt
Purity: ≥80% (HPLC)
Packaging: 5g
Price: $73.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: C3787
Product name: Chloramphenicol succinate sodium salt
Purity: ≥80% (HPLC)
Packaging: 25g
Price: $295
Updated: 2024/03/01

Sigma-Aldrich

Product number: C1425000
Product name: Chloramphenicol sodium succinate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: c1425000
Price: $90
Updated: 2024/03/01

Sigma-Aldrich

Product number: C3787
Product name: Chloramphenicol succinate sodium salt
Purity: ≥80% (HPLC)
Packaging: 100g
Price: $730
Updated: 2023/06/20

TRC

Product number: C325065
Product name: ChloramphenicolSuccinateSodium
Packaging: 25g
Price: $140
Updated: 2021/12/16

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Chloramphenicol sodium succinate Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white powder, hygroscopic

Uses

Chloramphenicol Succinate Sodium is a derivative of Chloramphenicol (C325030) which are broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.

Uses

Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weakly sodium hydroxide solutions. The sodium salt is the preferred formulation for pharmaceutical applications, providing a more readily soluble product. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

Uses

antibacterial, antirickettsial, inhibits protein synthesis

General Description

Chloramphenicol sodium succinate is the water-solublesodium salt of the hemisuccinate ester of chloramphenicol.Because of the low solubility of chloramphenicol, the sodiumsuccinate is preferred for intravenous administration. Theavailability of chloramphenicol from the ester followingintravenous administration is estimated to be 70% to 75%; theremainder is excreted unchanged. Poor availability ofthe active form from the ester following intramuscular injectionprecludes attaining effective plasma levels of the antibioticby this route. Orally administered chloramphenicol orits palmitate ester actually gives higher plasma levels of theactive antibiotic than does intravenously administered chloramphenicolsodium succinate. Nonetheless, effectiveconcentrations are achieved by either route.

General Description

White powder.

Air & Water Reactions

Freely soluble in water.

Fire Hazard

Flash point data for Chloramphenicol sodium succinate are not available, but Chloramphenicol sodium succinate is probably combustible.

Chloramphenicol sodium succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Chloramphenicol sodium succinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Chloramphenicol sodium succinate 982-57-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 500kg/month
Release date: 2021-07-23

Zhuozhou Wenxi import and Export Co., Ltd

Product: Chloramphenicol sodium succinate 982-57-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: Chloramphenicol sodium succinate 982-57-0
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-25

982-57-0, Chloramphenicol sodium succinateRelated Search:

Diphenyldimethoxysilane CHLOROPHOSPHONAZO III 4-Methoxyphenylacetone Disodium succinate Sodium benzoate Sodium acetate Sodium bicarbonate Diclofenac sodium Sodium hydroxide Dichlorodiphenylsilane Sodium gluconate Chloramphenicol hemisuccinate Phenyltriethoxysilane Chloramphenicol Sodium formate 6alpha-Methylprednisolone sodium succinate Dichloromethylphenylsilane Hydrocortisone sodium succinate

CHLORAMPHENICOL ALPHA-SUCCINATE SODIUM SALT

CHLORAMPHENICOL SODIUM SUCCINATE

CHLORAMPHENICOL SUCCINATE SODIUM

CHLORAMPHENICOL SUCCINATE SODIUM SALT

alpha-esterwithsodiumsuccinate

chloramphenicolmonosuccinatesodiumsalt

chloramphenicolsodiummonosuccinate

chloramphenicolsuccinatesodium*minimum80%(hpl

chloramphenicol-sukzinat-natrium

protophenicol

sodiumchloramphenicolsuccinate

CHLORAMPHENICOL SUCCINATE SODIUMMINIMUM 80% (HPLC)

Betamicetin

Butanedioic acid, mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester, monosodium salt

Butanedioic acid, mono[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester, monosodium salt, [R-(R*,R*)]-

Chloramphenicol sodium hemisuccinate

Chloromycetin sodium succinate

Clorofenicina

Cloromoin

D-Chloramphenicol sodium succinate

Levomycetin sodium succinate

Levomycetin-Nalcein

Mychel-S

Nalecin

Nevimycin

Sodium chloramphenical monosuccinate

Sodium chloramphenicol 3-succinate

Solnicol

Succinic acid, α-monoester with D-threo-(-)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide, monosodium salt (8CI)

CHLORAMPHENICOL,NASUCCINATE

Sodium 4-[2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate

Succinic acid 1-sodium 4-[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(p-nitrophenyl)propyl] ester salt

Succinic acid chloramphenicol sodium

Monosuccinate sodium salt

Sodium 4-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate

Chloramphenicol succinate sodium salt,Chloramphenicol α-succinate

CHLORAMPHENICOL SODIUM SOLUTION

Butanedioic acid,1-[(2R,3R)-2-[(2,2-dichloroacetyl)aMino]-3-hydroxy-3-(4-nitrophenyl)propyl]ester, sodiuM salt (1:1)

PubChem ID: 656580

Chloramphenicol sodium succinate CRS

Chloramphenicol Impurity 6

Chloramphenicol Sodium Succinate Sterile Powder for Injection

Chloramphenicol sodium succinat

Chloramphenicol Succinate Sodium (>90%)

Chloramphenicol succinate sodium, 10 mM in DMSO

982-57-0

C15H15Cl2N2O8Na

C15H15Cl2N2NaO8

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