Tetrahydro-2H-pyran-4-carbonyl chloride
- Product Name
- Tetrahydro-2H-pyran-4-carbonyl chloride
- CAS No.
- 40191-32-0
- Chemical Name
- Tetrahydro-2H-pyran-4-carbonyl chloride
- Synonyms
- Tetrahydro-2H-Pyran-4-Carbonyl;Trahydr-opyran-4-carbonyl chloride;4-(Chlorocarbonyl)tetrahydro-2H-pyran;Tetrahydro-pyran-4-carbonyl chloride;Tetrahydro-2H-pyrane-4-carbonylchloride;TETRAHYDRO-2H-PYRAN-4-CARBONYL CHLORIDE;2H-Pyran-4-carbonyl chloride, tetrahydro-;Tetrahydro-2H-pyran-4-carbonyl chloride 97%;tetrahydro-2H-pyran-4-carbonyl chloride Tetrahydro-2H-pyran-4-carbonyl chloride ,97%
- CBNumber
- CB0411990
- Molecular Formula
- C6H9ClO2
- Formula Weight
- 148.59
- MOL File
- 40191-32-0.mol
Tetrahydro-2H-pyran-4-carbonyl chloride Property
- Boiling point:
- 50 °C
- Density
- 1.201±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Colorless to Almost colorless
- InChIKey
- RYGUCYSSMOFTSH-UHFFFAOYSA-N
- CAS DataBase Reference
- 40191-32-0
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 14-20/21/22-29-34-36-52/53
- Safety Statements
- 23-24/25-36/37/39-45-26-61
- RIDADR
- 3265
- HazardClass
- IRRITANT
- HS Code
- 29339900
N-Bromosuccinimide Price
- Product number
- SYX00374
- Product name
- Tetrahydro-2H-pyran-4-carbonyl chloride
- Packaging
- 1g
- Price
- $286
- Updated
- 2025/07/31
- Product number
- T3890
- Product name
- Tetrahydro-2H-pyran-4-carbonyl Chloride
- Packaging
- 1G
- Price
- $62
- Updated
- 2025/07/31
- Product number
- T3890
- Product name
- Tetrahydro-2H-pyran-4-carbonyl Chloride
- Packaging
- 5G
- Price
- $213
- Updated
- 2025/07/31
- Product number
- T889583
- Product name
- Tetrahydro-2H-pyran-4-carbonyl Chloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 291404
- Product name
- Tetrahydro-2H-pyran-4-carbonyl chloride
- Packaging
- 500mg
- Price
- $340
- Updated
- 2021/12/16
Tetrahydro-2H-pyran-4-carbonyl chloride Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liquid
Synthesis
5337-03-1
40191-32-0
In a 50 mL three-necked round-bottomed flask, 6.85 g (52.6 mmol) of tetrahydropyran-4-carboxylic acid, 9.79 g (82.3 mmol) of thionyl chloride, and 10 mL of toluene were sequentially added, and a stirrer, thermometer, and reflux condenser were assembled. The reaction system was placed in an oil bath at 80 °C and the reaction was continuously stirred for 1.5 hours. At the end of the reaction, the solvent and excess thionyl chloride were removed by distillation under reduced pressure to afford 7.81 g (100% yield) of tetrahydropyran-4-carbonyl chloride as a light brown liquid. The product was characterized as follows: 1H-NMR (CDCl3, δ/ppm): 1.79-1.93 (2H, m), 1.99-2.06 (2H, m), 2.91-3.00 (1H, m), 3.40-3.49 (2H, m), 3.97-4.03 (2H, m); CI-MS (m/z): 131 [M+1]+.
References
[1] Patent: US2008/306287, 2008, A1. Location in patent: Page/Page column 6
[2] Patent: WO2008/71948, 2008, A2. Location in patent: Page/Page column 11-12
[3] Helvetica Chimica Acta, 1997, vol. 80, # 5, p. 1528 - 1551
[4] Journal of the Chemical Society, 1930, p. 2525,2529
[5] Chemical and Pharmaceutical Bulletin, 1987, vol. 35, # 6, p. 2426 - 2436
Tetrahydro-2H-pyran-4-carbonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tetrahydro-2H-pyran-4-carbonyl chloride manufacturers
- Product
- Tetrahydro-2H-pyran-4-carbonyl chloride 40191-32-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-29
- Product
- Tetrahydro-2H-pyran-4-carbonyl chloride 40191-32-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-09