ChemicalBook > CAS DataBase List > QX-314

QX-314

Product Name
QX-314
CAS No.
21306-56-9
Chemical Name
QX-314
Synonyms
QX-314;QX-314.Br;QX 314 BROMIDE;QX 314, 10 mM in DMSO;Lidocaine N-ethyl bromid;LIDOCAINE N-ETHYL BROMIDE;Lidocaine N-ethyl bromide;QX-314 - CAS 21306-56-9 - Calbiochem;QX-314 bromide (N-Ethyllidocaine bromide);LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT)
CBNumber
CB0421458
Molecular Formula
C16H27N2O+
Formula Weight
263.4
MOL File
21306-56-9.mol
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QX-314 Property

Melting point:
220 - 222°C
storage temp. 
Desiccate at RT
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
lyophilized solid
color 
White to Off-White
Water Solubility 
water: 3mg/mL
Specific Activity
40-60 Ci/mmol
Solvent
Ethanol:water (1:1)
Concentration
1 mCi/ml
Major Application
forensics and toxicology
pharmaceutical (small molecule)
veterinary
InChI
1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
InChIKey
DLHMKHREUTXMCH-UHFFFAOYSA-N
SMILES
[Br-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L5783
Product name
Lidocaine N-ethyl bromide
Purity
analytical standard, for drug analysis
Packaging
50mg
Price
$57.6
Updated
2025/07/31
Sigma-Aldrich
Product number
552233
Product name
QX-314
Packaging
100mg
Price
$146
Updated
2025/07/31
Sigma-Aldrich
Product number
L5783
Product name
Lidocaine N-ethyl bromide
Purity
analytical standard, for drug analysis
Packaging
250mg
Price
$293.55
Updated
2025/07/31
Tocris
Product number
1014
Product name
QX314bromide
Purity
≥99%(HPLC)
Packaging
100
Price
$125
Updated
2021/12/16
Usbiological
Product number
256388
Product name
QX 314 bromide
Packaging
100mg
Price
$385
Updated
2021/12/16
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QX-314 Chemical Properties,Usage,Production

Uses

Blocker of voltage-activated sodium channels

Uses

QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.

Biological Activity

Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.

QX-314 Preparation Products And Raw materials

Raw materials

Preparation Products

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QX-314 Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Ascent Scientific
Tel
4401179829988
Fax
4402030 700 369
Email
customerservice@ascentscientific.co.uk
Country
United Kingdom
ProdList
279
Advantage
60
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
HangZhou YuHao Chemical Technology Co., Ltd.
Tel
0571-82693216
Fax
0571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
2028
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58
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
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60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-(0)57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
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60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32470
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
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58

21306-56-9, QX-314Related Search:


  • 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium
  • QX-314;LIDOCAINE N-ETHYL BROMIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
  • QX-314.Br
  • QX-314 bromide (N-Ethyllidocaine bromide)
  • N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
  • N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE
  • QX-314
  • QX 314 BROMIDE
  • LIDOCAINE N-ETHYL BROMIDE
  • LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT)
  • QX-314 - CAS 21306-56-9 - Calbiochem
  • Lidocaine N-ethyl bromid
  • Lidocaine N ethyl bromide,Lidocaine Nethyl bromide
  • Ethanaminium,2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-
  • QX-314 bromide (N-Ethyllidocaine bromide), Na+ channel blocker
  • QX-314 bromide (N-Ethyllidocaine bromide) (mM/ml), Na+ channel blocker
  • QX 314, 10 mM in DMSO
  • Lidocaine <i>N</i>-ethyl bromide
  • 21306-56-9
  • C16H27BrN2O
  • C16H27N2OBr
  • C16H27N2O
  • A quaternary derivative of lidocaine that is not membrane permeable. Blocks both fast Na+-dependent action potentials and voltage-dependent, non-inactivating Na+ conductance.
  • Analytical Chromatography Product Catalog
  • Analytical Standards
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  • Sodium channel
  • Ion Channels