ChemicalBook > CAS DataBase List > QX-314

QX-314

Product Name
QX-314
CAS No.
21306-56-9
Chemical Name
QX-314
Synonyms
QX-314;QX-314.Br;QX 314 BROMIDE;QX 314, 10 mM in DMSO;Lidocaine N-ethyl bromid;LIDOCAINE N-ETHYL BROMIDE;QX-314 - CAS 21306-56-9 - Calbiochem;QX-314 bromide (N-Ethyllidocaine bromide);LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT);Lidocaine N ethyl bromide,Lidocaine Nethyl bromide
CBNumber
CB0421458
Molecular Formula
C16H27N2O+
Formula Weight
263.4
MOL File
21306-56-9.mol
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QX-314 Property

Melting point:
220 - 222°C
storage temp. 
Desiccate at RT
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
lyophilized solid
color 
White to Off-White
Water Solubility 
water: 3mg/mL
Specific Activity
40-60 Ci/mmol
Solvent
Ethanol:water (1:1)
Concentration
1 mCi/ml
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L5783
Product name
Lidocaine N-ethyl bromide
Purity
analytical standard, for drug analysis
Packaging
50mg
Price
$56.5
Updated
2024/03/01
Sigma-Aldrich
Product number
552233
Product name
QX-314
Packaging
100mg
Price
$142
Updated
2024/03/01
Alfa Aesar
Product number
J60678
Product name
Lidocaine N-ethyl bromide, 99+%
Packaging
100mg
Price
$104.65
Updated
2024/03/01
Sigma-Aldrich
Product number
L5783
Product name
Lidocaine N-ethyl bromide
Purity
analytical standard, for drug analysis
Packaging
250mg
Price
$225
Updated
2024/03/01
Tocris
Product number
1014
Product name
QX314bromide
Purity
≥99%(HPLC)
Packaging
100
Price
$125
Updated
2021/12/16
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QX-314 Chemical Properties,Usage,Production

Uses

Blocker of voltage-activated sodium channels

Uses

QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.

Biological Activity

Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.

QX-314 Preparation Products And Raw materials

Raw materials

Preparation Products

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QX-314 Suppliers

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21306-56-9, QX-314Related Search:


  • 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium
  • QX-314;LIDOCAINE N-ETHYL BROMIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
  • QX-314.Br
  • QX-314 bromide (N-Ethyllidocaine bromide)
  • N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE
  • N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE
  • QX-314
  • QX 314 BROMIDE
  • LIDOCAINE N-ETHYL BROMIDE
  • LIDOCAINE N-ETHYL BROMIDE (QUATERNARY SALT)
  • QX-314 - CAS 21306-56-9 - Calbiochem
  • Lidocaine N-ethyl bromid
  • Lidocaine N ethyl bromide,Lidocaine Nethyl bromide
  • Ethanaminium,2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-
  • QX-314 bromide (N-Ethyllidocaine bromide), Na+ channel blocker
  • QX-314 bromide (N-Ethyllidocaine bromide) (mM/ml), Na+ channel blocker
  • QX 314, 10 mM in DMSO
  • 21306-56-9
  • C16H27BrN2O
  • C16H27N2OBr
  • C16H27N2O
  • A quaternary derivative of lidocaine that is not membrane permeable. Blocks both fast Na+-dependent action potentials and voltage-dependent, non-inactivating Na+ conductance.
  • Analytical Chromatography Product Catalog
  • Analytical Standards
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  • Sodium channel
  • Ion Channels