L-KAWAIN

Product Name: L-KAWAIN
CAS No.: 500-64-1
Chemical Name: L-KAWAIN
Synonyms: KAWAIN;gonosan;L-KAWAIN;Nsc112162;(R)-KAWAIN;(R)-(+)-Kavain;Kawain (200 mg);L-KAWAIN USP/EP/BP;5,6-Dihydro-4-methoxy-6-styryl-2-pyron;5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one
CBNumber: CB0182759
Molecular Formula: C14H14O3
Formula Weight: 230.26
MOL File: 500-64-1.mol

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L-KAWAIN Property

Melting point:: 142-148℃
alpha: D20 +105° (abs alc)
Boiling point:: bp0.1 195-197°
Density: 1.1914 (rough estimate)
refractive index: 1.5557 (estimate)
storage temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form: Solid
color: White to Light Yellow
Stability:: Light Sensitive
LogP: 0.784 (est)

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2932202000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26524
Product name: Kavain
Packaging: 50mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 26524
Product name: Kavain
Packaging: 100mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 26524
Product name: Kavain
Packaging: 10mg
Price: $32
Updated: 2024/03/01

TRC

Product number: K145700
Product name: Kawain
Packaging: 100mg
Price: $160
Updated: 2021/12/16

TRC

Product number: K145700
Product name: Kawain
Packaging: 200mg
Price: $265
Updated: 2021/12/16

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L-KAWAIN Chemical Properties,Usage,Production

Originator

Largon,Klinge

Uses

Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction.

Definition

ChEBI: Kawain is a member of 2-pyranones and an aromatic ether.

Manufacturing Process

To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g bromosuccinimide. After cooling to the mixture was added 300 ml of carbon tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid, 700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared (R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C, yield 60-70%.

Therapeutic Function

Anesthetic; Tranquilizer

L-KAWAIN Preparation Products And Raw materials

Raw materials

Preparation Products

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L-KAWAIN Suppliers

China 87 India 1 United Kingdom 6 United States 14 USA 1 Global 109

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 3401
Advantage: 50

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

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View Lastest Price from L-KAWAIN manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd

Product: L-KAWAIN 500-64-1
Price: US $0.00-0.00/mg
Min. Order: 5mg
Purity: 99%
Supply Ability: 40kg
Release date: 2023-02-10

Shanghai Standard Technology Co., Ltd.

Product: Kawain 500-64-1
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-27

Career Henan Chemical Co

Product: L-KAWAIN 500-64-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-17

500-64-1, L-KAWAINRelated Search:

Tetracaine hydrochloride Aconitine VERATRIDINE TETRODOTOXIN QX-314 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5<br>-dimethoxyphenylamide CLINODISIDE A N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride SDZ-201 106 (+/-) PD 85639 BATRACHOTOXIN DL-KAWAIN,KAWAIN 5,6-DIHYDRO-2H-PYRAN-2-ONE 4-phenyl-3-buten-2-ol 5,6-DIHYDRO-4-METHOXY-2H-PYRAN 5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE L-KAWAIN PARASORBICACID

6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on

gonosan

(R)-(+)-Kavain

[R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one

5,6-Dihydro-4-methoxy-6-styryl-2-pyron

(6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one

(R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one

2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]-

2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)-

2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)-

Nsc112162

5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one

Kawain (200 mg)

KAWAIN

L-KAWAIN

(R)-KAWAIN

(r)-5,6-dihydro-4-methoxy-6-styryl-2h-pyran-2-one

4-methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone

5-hydroxy-3-methoxy-7-phenyl-2,6-heptadienoicacidgamma-lactone

2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)-

L-KAWAIN USP/EP/BP

(R,E)-4-Methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one

TIANFU-CHEM_2H-Pyran-2-one,5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- 500-64-1

γ-Aminobutyric acid Receptor,Calcium Channel,inhibit,Inhibitor,GABA Receptor,Gamma-aminobutyric acid Receptor,Na channels,Sodium Channel,Ca2+ channels,Ca channels,(+)-Kavain,(+) Kavain,Na+ channels,(+)Kavain

500-64-1

500-61-4

315-48-4

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