ChemicalBook > CAS DataBase List > AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]

AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]

Product Name
AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]
CAS No.
9001-66-5
Chemical Name
AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]
Synonyms
AOC3;SSAO;KAOD;Renalase;Tyraminase;VAP-1 human;MAO (enzyme);E.C. 1.4.3.4;TYRAMINE OXIDASE;Spermine oxidase
CBNumber
CB0445553
Molecular Formula
C7H15N2O6P
Formula Weight
254.177561
MOL File
9001-66-5.mol
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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Property

Density 
0.319[at 20℃]
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
form 
lyophilized powder
color 
White to off-white
biological source
human
Water Solubility 
102g/L at 30℃
InChI
InChI=1/C7H15N2O6P/c8-5(7(11)12)2-1-3-9-6(10)4-16(13,14)15/h5H,1-4,8H2,(H,9,10)(H,11,12)(H2,13,14,15)/t5-/s3
InChIKey
FCIHAQFHXJOLIF-GQMHJJTINA-N
SMILES
C(O)(=O)[C@@H](N)CCCNC(CP(O)(O)=O)=O |&1:3,r|
LogP
-3 at 23℃
CAS DataBase Reference
9001-66-5
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP3295
Product name
VAP-1 human
Purity
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
Packaging
10μG
Price
$367
Updated
2025/07/31
Sigma-Aldrich
Product number
SRP6241
Product name
VAP-1 human
Purity
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE)
Packaging
10μG
Price
$363
Updated
2024/03/01
Usbiological
Product number
028151
Product name
Spermine Oxidase
Packaging
96Tests
Price
$864
Updated
2021/12/16
Usbiological
Product number
028152
Product name
Spermine Oxidase
Packaging
96Tests
Price
$879
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ENZ0000762
Product name
TYRAMINE OXIDASE
Purity
95.00%
Packaging
5MG
Price
$502.41
Updated
2021/12/16
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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Chemical Properties,Usage,Production

Uses

Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions[1][2].

Definition

An enzyme that is distributedwidely among animals. It inactivates a number ofbiogenic amines by catalyzing the oxidative deam-ination of these compounds.

Flammability and Explosibility

Not classified

Biological Activity

The protein VAP-1 (vascular adhesion protein-1) belongs to the group of semicarbazide sensitive amine oxidases (SSAO) th at catalyze the formation of reactive oxygen species. It is a unique adhesion molecule th at participates in inflammatory leukocyte recruitment in blood vessels. It functions in leukocyte extravasation to inflamed tissues. In the human eye, it has been associated with ocular inflammatory diseases, such as uveitis, age-related macular degeneration, and diabetic retinopathy. Its expression has been observed to be altered in several diseases, such as rheumatoid arthritis, diabetes, and atherosclerosis.

References

[1] Shih JC, et al. Monoamine oxidase: from genes to behavior. Annu Rev Neurosci. 1999;22:197-217. DOI:10.1146/annurev.neuro.22.1.197
[2] Bortolato M, et al. Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1527-33. DOI:10.1016/j.addr.2008.06.002
[3] Youdim MB, et al. The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci. 2006 Apr;7(4):295-309. DOI:10.1038/nrn1883

AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Preparation Products And Raw materials

Raw materials

Preparation Products

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AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING] Suppliers

China 74 Germany 1 Switzerland 1 United States 5 Global 81
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9001-66-5, AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]Related Search:

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  • AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING]
  • TYRAMINE OXIDASE
  • PLASMA AMINE OXIDASE FROM BOVINE PLASMA;PAO
  • amine oxidase, flavin-containing
  • plasma amine oxidase from bovine plasma
  • tyramine oxidase from arthrobacter*species
  • Oxidase, monoamine
  • YRAMINE OXIDASE FROM ARTHROBACTER &
  • tyramine oxidase from arthrobacter sp.
  • SSAO
  • AOC3
  • VAP-1 human
  • Epinephrine oxidase
  • Flavin amine oxidase
  • MAO (enzyme)
  • Monoamine oxygenase
  • N1,N12-Diacetylspermine oxidase
  • Renalase
  • Serotonin deaminase
  • Spermidine oxidase
  • Spermine oxidase
  • Tryptamine oxidase
  • Tyraminase
  • E.C. 1.4.3.4
  • KAOD
  • Monoamine Oxidase Activity Microplate Assay Kit
  • 9001-66-5
  • BioChemical
  • General Metabolic Enzymes I-Z
  • General Metabolic Enzymes
  • Metabolomics