application
ChemicalBook > CAS DataBase List > 2,4,5-Triamino-6-hydroxypyrimidine sulfate

2,4,5-Triamino-6-hydroxypyrimidine sulfate

application
Product Name
2,4,5-Triamino-6-hydroxypyrimidine sulfate
CAS No.
35011-47-3
Chemical Name
2,4,5-Triamino-6-hydroxypyrimidine sulfate
Synonyms
2,5,6-Triamino-4(1H)-pyrimidinone sulfate;2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE HYDRATE;TAPOS;4-Hydr;NSC 167378;Folic acid Impurity 69;Folic Acid Impurity 26;Folic Acid Impurity B Sulfate;Folic Acid EP Impurity B Sulfate;4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE
CBNumber
CB0447678
Molecular Formula
C4H9N5O5S
Formula Weight
239.21
MOL File
35011-47-3.mol
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2,4,5-Triamino-6-hydroxypyrimidine sulfate Property

Melting point:
≥300 °C(lit.)
RTECS 
UW7175000
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO.
form 
Solid
color 
Pale Yellow
InChI
InChI=1S/C4H7N5O.H2O4S/c5-1-2(6)8-4(7)9-3(1)10;1-5(2,3)4/h5H2,(H5,6,7,8,9,10);(H2,1,2,3,4)
InChIKey
RSKNEEODWFLVFF-UHFFFAOYSA-N
SMILES
NC1C(N=C(N)NC=1N)=O.S(O)(O)(=O)=O
CAS DataBase Reference
35011-47-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2001
Product name
Folic Acid Impurity B
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
20MG
Price
$647
Updated
2024/03/01
TCI Chemical
Product number
T0335
Product name
2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate
Purity
>90.0%(T)
Packaging
25g
Price
$38
Updated
2024/03/01
Alfa Aesar
Product number
B21989
Product name
2,4,5-Triamino-6-hydroxypyrimidine sulfate, 97%
Packaging
25g
Price
$49.65
Updated
2024/03/01
Alfa Aesar
Product number
B21989
Product name
2,4,5-Triamino-6-hydroxypyrimidine sulfate, 97%
Packaging
100g
Price
$152.65
Updated
2024/03/01
TRC
Product number
H971250
Product name
6-Hydroxy-2,4,5-triaminopyrimidine,Sulfate
Packaging
1g
Price
$100
Updated
2021/12/16
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2,4,5-Triamino-6-hydroxypyrimidine sulfate Chemical Properties,Usage,Production

application

6-Hydroxy-2,4,5-triaminopyrimidine, Sulfate (cas# 35011-47-3) is a compound useful in organic synthesis.

Chemical Properties

yellow-beige crystalline powder

Uses

2,4,5-Triamino-6-hydroxypyrimidine Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity.

Uses

2,4,5-Triamino-6-hydroxypyrimidine sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities.

Purification Methods

This salt has very low solubility in H2O. It is best purified by conversion into the dihydrochloride salt, which is then re-converted to the insoluble sulfate salt. The sulfate salt (2.57g, 10mmoles) is suspended in H2O (20mL) containing BaCl2 (10mmoles) and stirred in a boiling water bath for 15minutes. After cooling, the insoluble BaSO4 is filtered off and washed with boiling H2O (10mL). The combined filtrate and washings are made acidic with HCl and evaporated to dryness. The residual hydrochloride salt is recrystallised from H2O by adding conc HCl whereby the dihydrochloride salt separates as clusters which darken at 260o and dec > 300o[darkening > 360o]. [Baugh & Shaw J Org Chem 29 3610 1964, King & Spengley J Chem Soc 2144 1952]. The hydrochloride is then dissolved in H2O, and while hot an equivalent of H2SO4 is added when the sulfate separates as a white microcrystalline solid which is filtered off washed liberally with H2O and dried in vacuum over P2O5. [Albert & Wood J Appl Chem London 3 521 1953, UV: Cavalieri et al. J Am Chem Soc 70 3875 1948; see also Pfleiderer Chem Ber 90 2272 1957, Traube Chem Ber 33 1371 1900.] The hydrochloride has m > 300o. [Beilstein 25 II 384, 25 III/IV 3648.]

2,4,5-Triamino-6-hydroxypyrimidine sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,5-Triamino-6-hydroxypyrimidine sulfate Suppliers

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View Lastest Price from 2,4,5-Triamino-6-hydroxypyrimidine sulfate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-11-26
Shanghai Joiny Pharmaceutical Co.,LTD
Product
2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-12-04
Hebei Mojin Biotechnology Co.,Ltd
Product
2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-05

35011-47-3, 2,4,5-Triamino-6-hydroxypyrimidine sulfateRelated Search:

Lithium bis(trimethylsilyl)amide Neomycin sulfate Tris(hydroxymethyl)aminomethane Nitrilotriacetic acid 4-Hydroxy-6-aminopyrimidine Ammonium sulfate Magnesium sulfate heptahydrate Sodium sulfate Potassium sulfate 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE Colistin sulfate Ferrous sulfate monohydrate calcium sulfate D-Glucosamine sulfate Heparitin, sulfate sulfate 2-Amino-7-(chloromethyl)pteridin-4(1H)-one

  • 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE SULFATE HYDRATE
  • 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE HYDRATE
  • 2,5,6-TRIAMINO-4(1H)-PYRIMIDINONE SULFATE HYDRATE
  • 4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE
  • 2,5,6-Triamino-4(1H)-pyrimidinone sulfate
  • 4-hydroxy-2,5,6-triaminopyrimidine sulf. monohydr. (6-2,4,5)
  • 2,5,6-triamino-4-pyrimidol sulfate salt
  • 4-hydroxy-2,5,6-triaminopyrimidine sulfate salt
  • 2,4,5-triamido-6-oxhydrylpyrimidine sulfate
  • 4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE SULFATE 97+%
  • 2,4,5-Triamino-6-hydroxypyrimidine sulfate
  • 2,5,6-Triamino-4-pyrimidol sulfate
  • 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate
  • 6-Hydroxy-2,4,5-triaminopyrimidine sulfate,97%
  • 4-Hydr
  • 2,5,6-TriaMino-4(3H)-pyriMidinone Sulfate
  • NSC 167378
  • 2,5,6-TriaMinopyriMidin-4(3H)-one sulfate
  • 2,5,6-Triaminopyrimidin-4-ol sulphate, 4-Hydroxy-2,5,6-triamino-1,3-diazine sulphate
  • 4-Hydroxy-2,5,6-triaminopyrimidine sulphate
  • 4-Hydroxy-2,5,6-triaminopyrimidine sulfate salt, >=97%
  • 2,4,5-triamino-6-hydroxypyrimidine sulfate:2,5,6-triamino-4-pyrimidol sulfate
  • 2,5,6-Triaminopyrimidin-4(1H)-one Sulfate
  • 2,4,5 -TRIAMINO-6-HYDROXY PYRIMIDINE SULFATE 93% MIN
  • 5-Triamino-6-hydroxypyrimidine sulfate
  • Folic acid Impurity 69
  • Folic Acid EP Impurity B Sulfate
  • 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate&gt
  • 4(1H)-Pyrimidinone, 2,5,6-triamino-, sulfate (1:1) (9CI)
  • 2,4,5-Triamino-6-hydroxypyrimidine sulfate ISO 9001：2015 REACH
  • 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Salt Discontinued See: T767240 and H971250
  • Folic Acid Impurity B Sulfate
  • 4-hydroxy-2,5,6-triaminopyrimidine sulf. monohydr
  • Folic Acid Impurity 26
  • TAPOS
  • 4(3H)-Pyrimidinone, 2,5,6-triamino-, sulfate (1:1)
  • 2,5,6-triamino-4(3H)-Pyrimidinone sulfate (1:1)
  • Folic Acid Impurity 2 Sulfate(Folic Acid EP Impurity B Sulfate)
  • 6-hydroxy-2,4,5-triaminopyrimiddine sutfate
  • 35011-47-3
  • C4H7N5OH2OH2O4S
  • C4H11N5O6S
  • Building Blocks
  • Pyrimidines
  • Heterocyclic Building Blocks
  • Heterocyclic Compounds