ChemicalBook > CAS DataBase List > L(+)-Diethyl L-tartrate
L(+)-Diethyl L-tartrate
- Product Name
- L(+)-Diethyl L-tartrate
- CAS No.
- 87-91-2
- Chemical Name
- L(+)-Diethyl L-tartrate
- Synonyms
- DET;DIETHYL TARTRATE;L-DET;DIETHYL L-TARTRATE;Diethyl (2R,3R)-tartrate;diethyl tartarate;(2S,3S)-diethyl 2,3-dihydroxysuccinate;Diethyl (2R,3R)-2,3-dihydroxybutanedioate;FEMA 2378;-tartrate
- CBNumber
- CB0456290
- Molecular Formula
- C8H14O6
- Formula Weight
- 206.19
- MOL File
- 87-91-2.mol
More
Less
L(+)-Diethyl L-tartrate Property
- Melting point:
- 17 °C
- Boiling point:
- 280 °C (lit.)
- alpha
- 7.5 º (neat)
- Density
- 1.204 g/mL at 25 °C (lit.)
- vapor pressure
- 0.402Pa at 25℃
- refractive index
- n20/D 1.446(lit.)
- FEMA
- 2378 | DIETHYL TARTRATE
- Flash point:
- 200 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Water (Slightly)
- pka
- 11.61±0.20(Predicted)
- form
- Viscous Liquid
- color
- Clear
- Odor
- at 100.00 %. mild fruity wine caramellic
- Odor Type
- fruity
- biological source
- synthetic
- optical activity
- [α]20/D +8.5°, neat
- Water Solubility
- insoluble
- JECFA Number
- 622
- Merck
- 14,3855
- BRN
- 1727145
- Dielectric constant
- 4.5（20℃）
- InChIKey
- YSAVZVORKRDODB-PHDIDXHHSA-N
- LogP
- 0.2 at 25℃
- CAS DataBase Reference
- 87-91-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Diethyl tartrate(87-91-2)
- EPA Substance Registry System
- Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, 1,4-diethyl ester (87-91-2)
More
Less
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29181300
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W237809
- Product name
- Diethyl <SC>L</SC>-tartrate
- Purity
- ≥99%, FG
- Packaging
- 1 unit
- Price
- $54.6
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W237809
- Product name
- Diethyl <SC>L</SC>-tartrate
- Purity
- ≥99%, FG
- Packaging
- 1 unit
- Price
- $54.6
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W237809
- Product name
- Diethyl L-tartrate
- Purity
- ≥99%, FG
- Packaging
- 100g
- Price
- $74.95
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W237809
- Product name
- Diethyl L-tartrate
- Purity
- ≥99%, FG
- Packaging
- 1kg
- Price
- $239
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W237809
- Product name
- Diethyl L-tartrate
- Purity
- ≥99%, FG
- Packaging
- 5kg
- Price
- $846
- Updated
- 2025/07/31
More
Less
L(+)-Diethyl L-tartrate Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liqui
Chemical Properties
Diethyl tartrate has a mild, fruity, wine aroma.
Occurrence
The d-isomer has not been reported found in nature; the l-isomer and the racemic form are of little importance. Reported found in sherry, white and red wine.
Uses
(+)-Diethyl L-tartrate is used as a chiral auxiliary in the Sharpless enantioselective epoxidation of allylic alcohols, for Sharpless-type enantioselective oxidation of sulfides to sulfoxides and as a chiral auxiliary in the enantioselective construction of cyclopropanes from allylic alcohols by an asymmetric Simmons-Smith reaction. It is also used as a chiral reagent in a host of chemical reactions, such as the synthesis of isoquinoline alkaloids and arundic acid, which has been used in acute ischemic stroke therapy.
Uses
(+)-Diethyl L-tartrate can be used in the synthesis of biologically active compounds such as (+)-altholactone, (-)-aspicilin, (+)-monomorine I and (+)-(1R,2R,3S,6S)-3,6-di-O-methyl conduritol-E.
Uses
Diethyl L-(+)-Tartrate is used as a chiral reagent in a host of chemical reactions, such as the synthesis of isoquinoline alkaloids and arundic acid, which has been used in acute ischemic stroke thera py.
General Description
Made from natural tartaric acid
Flammability and Explosibility
Non flammable
Synthesis
64-17-5
87-69-4
87-91-2
(1) 30 g of L-(+)-tartaric acid was added to a 500 mL three-necked flask followed by 150 mL of anhydrous ethanol. The stirrer was turned on to make the mixture homogeneously mixed, and the reaction temperature was controlled in the range of 0 to 30 °C. 95.4 g of thionyl chloride was slowly added dropwise for 1.5 h, taking care to control the rate of dropwise acceleration to manage the exothermic process. After the dropwise addition, the reaction system was warmed up to 50 °C and the reaction was continued for 2 hours. After completion of the reaction, ethanol was removed by distillation under reduced pressure to obtain the crude product of diethyl L-(+)-tartarate. (2) To the above crude product, 3.3 g of potassium bicarbonate was added, the temperature was raised to 20 °C and the reaction was stirred for 3 hours. At the end of the reaction, the solid insoluble matter was removed by filtration to obtain 39.6 g of L-(+)-diethyl L-tartrate, and the product was a colorless or light yellow oily liquid with a molar yield of 96.2%. The purity of the product was tested to be 99.4%.
References
[1] Tetrahedron Letters, 2013, vol. 54, # 36, p. 4851 - 4853
[2] RSC Advances, 2015, vol. 5, # 15, p. 11687 - 11696
[3] Patent: CN107337603, 2017, A. Location in patent: Paragraph 0025; 0026; 0027; 0028; 0029; 0030; 0031-0040
[4] Journal of Organic Chemistry, 2012, vol. 77, # 19, p. 8465 - 8479,15
[5] Patent: CN106966943, 2017, A. Location in patent: Paragraph 0090; 0091
L(+)-Diethyl L-tartrate Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
L(+)-Diethyl L-tartrate Suppliers
- Tel
- 021-021-64975436 18917636693
- Fax
- 021-24280809
- 1377976036@qq.com
- Country
- China
- ProdList
- 308
- Advantage
- 55
- Tel
- 021-69185552 13701777608
- Fax
- 021-69186006
- kangtuochem@163.com
- Country
- China
- ProdList
- 4232
- Advantage
- 55
- Tel
- 021-58892003
- info@qiaochem.com
- Country
- China
- ProdList
- 6059
- Advantage
- 65
- Tel
- 028-85247892 18980630336;
- zhenzhenge@lkchiralchina.com
- Country
- China
- ProdList
- 45
- Advantage
- 58
- Tel
- 027-87182908 18064088908
- Fax
- 027-87182900
- 65824125@qq.com
- Country
- China
- ProdList
- 96
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 15527621225
- 1791901229@qq.com
- Country
- China
- ProdList
- 6945
- Advantage
- 52
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 021-50460086-9 15921403865
- Fax
- +86-21-50462321
- han_yajun@dctc.daicel.com
- Country
- China
- ProdList
- 7471
- Advantage
- 65
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11705
- Advantage
- 57
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3199
- Advantage
- 55
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9718
- Advantage
- 55
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12335
- Advantage
- 58
- Tel
- 400-810-7969 010-59572699
- Fax
- 010-59572688
- ningzi.li@inno-chem.com.cn
- Country
- China
- ProdList
- 6134
- Advantage
- 55
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- +86 518-83616958 +86 519-82884848 (0)13861113988
- Fax
- +86 518-83616928 : +86 519-82835618
- postmaster@chiral-compounds.com
- Country
- China
- ProdList
- 20
- Advantage
- 74
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9546
- Advantage
- 55
- Tel
- 86-0755-86635001
- Fax
- 86-0755-22642228
- cantotech@126.com
- Country
- China
- ProdList
- 4566
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- +86 0510-85629785
- Fax
- +86 0510-85625359
- Country
- China
- ProdList
- 2327
- Advantage
- 58
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9979
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
More
Less
View Lastest Price from L(+)-Diethyl L-tartrate manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- L(+)-Diethyl L-tartrate 87-91-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-11-14
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- L(+)-Diethyl L-tartrate 87-91-2
- Price
- US $200.00-85.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-23
Henan Aochuang Chemical Co.,Ltd.
- Product
- L(+)-Diethyl L-tartrate 87-91-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-13
87-91-2, L(+)-Diethyl L-tartrateRelated Search:
Diethyl malonate
Methyl acrylate
Diethyl oxalate
L(+)-Tartaric acid
Tris(trimethylsilyl)phosphate
(-)-Dimethyl D-tartrate
Ethyl bromodifluoroacetate
Diethyl methylmalonate
Diethyl carbonate
Diethyl sulfate
Mefenpyr-diethyl
Tylosin tartrate
Diethyl phthalate
D(-)-Tartaric acid
Diethyl azodicarboxylate
Diethyl maleate
Squaric acid
Perfluoro-2-methyl-2-pentene
Diethyl Tartrate