ChemicalBook > CAS DataBase List > BMS-1001
BMS-1001
- Product Name
- BMS-1001
- CAS No.
- 2113650-03-4
- Chemical Name
- BMS-1001
- Synonyms
- BMS-1001;BMS 1001,BMS1001;2113650-03-4 (free base);D-Serine, N-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-
- CBNumber
- CB04667652
- Molecular Formula
- C35H34N2O7
- Formula Weight
- 594.65
- MOL File
- 2113650-03-4.mol
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BMS-1001 Property
- Boiling point:
- 801.2±65.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mg/mL (84.08 mM);Ethanol: Insoluble
- pka
- 2.08±0.10(Predicted)
- Water Solubility
- Water: Insoluble
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC22928
- Product name
- BMS-1001
- Purity
- >98%
- Packaging
- 100mg
- Price
- $750
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC22928
- Product name
- BMS-1001
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1350
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC22928
- Product name
- BMS-1001
- Purity
- >98%
- Packaging
- 1g
- Price
- $2700
- Updated
- 2021/12/16
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BMS-1001 Chemical Properties,Usage,Production
Uses
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction (IC50: 2.25 nM in a homogeneous time-resolved fluorescence binding assay).
Biological Activity
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. It attenuates the inhibitory effect of soluble PD-L1 on T cell receptor-mediated T lymphocyte activation.
target
Target | Value |
PD-1/PD-L1 (Cell-free assay) | 253 nM(EC50) |
BMS-1001 Preparation Products And Raw materials
Raw materials
Preparation Products
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2113650-03-4, BMS-1001Related Search:
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