ChemicalBook > CAS DataBase List > BMS-1001

BMS-1001

Product Name
BMS-1001
CAS No.
2113650-03-4
Chemical Name
BMS-1001
Synonyms
BMS-1001;BMS 1001,BMS1001;2113650-03-4 (free base);D-Serine, N-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-
CBNumber
CB04667652
Molecular Formula
C35H34N2O7
Formula Weight
594.65
MOL File
2113650-03-4.mol
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BMS-1001 Property

Boiling point:
801.2±65.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/mL (84.08 mM);Ethanol: Insoluble
pka
2.08±0.10(Predicted)
Water Solubility 
Water: Insoluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC22928
Product name
BMS-1001
Purity
>98%
Packaging
100mg
Price
$750
Updated
2021/12/16
DC Chemicals
Product number
DC22928
Product name
BMS-1001
Purity
>98%
Packaging
250mg
Price
$1350
Updated
2021/12/16
DC Chemicals
Product number
DC22928
Product name
BMS-1001
Purity
>98%
Packaging
1g
Price
$2700
Updated
2021/12/16
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BMS-1001 Chemical Properties,Usage,Production

Uses

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction (IC50: 2.25 nM in a homogeneous time-resolved fluorescence binding assay).

Biological Activity

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. It attenuates the inhibitory effect of soluble PD-L1 on T cell receptor-mediated T lymphocyte activation.

target

TargetValue
PD-1/PD-L1
(Cell-free assay)
253 nM(EC50)

BMS-1001 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMS-1001 Suppliers

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2113650-03-4, BMS-1001Related Search:


  • BMS-1001
  • D-Serine, N-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-
  • 2113650-03-4 (free base)
  • BMS 1001,BMS1001
  • 2113650-03-4
  • 113650-03-4