4-FLUORO-2-IODOBENZOIC ACID
- Product Name
- 4-FLUORO-2-IODOBENZOIC ACID
- CAS No.
- 56096-89-0
- Chemical Name
- 4-FLUORO-2-IODOBENZOIC ACID
- Synonyms
- BUTTPARK 83\07-33;4-FLUORO-2-IODOBENZOIC ACID;2-Iodo-4-fluorobenzoic acid;Benzoic acid,4-fluoro-2-iodo-;4-Fluoro-2-iodobenzoicacid99%;4-Fluoro-2-iodobenzoic acid 99%;4-FLUORO-2-IODOBENZOIC ACID ISO 9001：2015 REACH
- CBNumber
- CB0472526
- Molecular Formula
- C7H4FIO2
- Formula Weight
- 266.01
- MOL File
- 56096-89-0.mol
4-FLUORO-2-IODOBENZOIC ACID Property
- Melting point:
- 143-147 °C
- Boiling point:
- 309.4±27.0 °C(Predicted)
- Density
- 2.074±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 2.80±0.10(Predicted)
- form
- Solid
- color
- White
- Sensitive
- Light Sensitive
- InChIKey
- DUKFTVLJAXWGPI-UHFFFAOYSA-N
- CAS DataBase Reference
- 56096-89-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 25-36/37/38
- Safety Statements
- 26-36/37-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 678910
- Product name
- 4-Fluoro-2-iodobenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $28.35
- Updated
- 2025/07/31
- Product number
- F591998
- Product name
- 4-Fluoro-2-iodobenzoic acid
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC2698
- Product name
- 4-Fluoro-2-iodobenzoic acid
- Purity
- 99%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 2621-K-42
- Product name
- 4-Fluoro-2-iodobenzoic acid
- Purity
- 99%
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- X4488
- Product name
- 4-Fluoro-2-iodobenzoic acid
- Packaging
- 1g
- Price
- $84
- Updated
- 2021/12/16
4-FLUORO-2-IODOBENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
Off-white crystalline
Uses
4-Fluoro-2-iodobenzoic Acid is a reagent used in organic synthesis including amixile-based inhibitors of the pyruvate-ferredoxin oxidoreductases of anaerobic bacteria.
Synthesis
909545-47-7
56096-89-0
Synthesis of 4-fluoro-2-iodobenzoic acid (11): 4-fluoro-2-iodobenzaldehyde (10) (2.82 g, 11.3 mmol) was dissolved in a mixed solvent of H2O (500 mL) and acetone (90 mL), to which were added sequentially H2NSO3H (1.59 g, 16.4 mmol) and NaClO2 (1.78 g, 15.7 mmol, technical grade (80% purity). The reaction mixture was stirred at room temperature for 3.5 h. The progress of the reaction was monitored by thin layer chromatography (TLC) until complete consumption of the ingredients. Upon completion of the reaction, the aqueous phase was extracted with ethyl acetate (EtOAc, 4×), the organic phases were combined, washed with saturated saline, and concentrated under reduced pressure to afford the colorless solid product 11 (2.55 g, 9.6 mmol, 85% yield). The product was characterized by the following data: melting point 155-157 °C; TLC Rf = 0.5 (CHCl3-MeOH = 10:1, v/v); IR (KBr, cm-1): 3436 (br), 3070 (br), 1701 (s), 1588 (s), 1575 (s), 1477 (m), 1413 (m), 1303 (s). 1260 (s), 1206 (s), 1030 (m), 874 (m), 605 (m); 1H NMR (300 MHz, CD3OD): δ 7.23-7.29 (m, 1H), 7.82 (dd, 3JHF = 8.4 Hz, 4JHH = 2.6 Hz, 1H), 7.90 (dd, 3JHH = 8.7 Hz, 4JHH = 2.6 Hz, 1H), 7.90 (dd, 3JHH = 8.7 Hz, 4JHH = 6.0 Hz), 7.90 (dd, 3JHH = 8.7 Hz, 4JHH = 2.6 Hz, 1H) 4JHF = 6.0 Hz, 1H); 13C NMR (75.5 MHz, CD3OD): δ 95.4 (d, 3JCF = 8.5 Hz), 116.4 (d, 2JCF = 21.7 Hz), 129.7 (d, 2JCF = 24.1 Hz), 133.8 (d, 4JCF = 3.5 Hz), 134.0 (d, 3JCF = 9.1 Hz), 164.9 (d, 1JCF = 255.7 Hz), 169.0; MS (EI) m/z (relative intensities): 267 (27) [M+ + H], 266 (100) [M+], 249 (75) [C7H3OFI+], 221 (13) [C6H3FI+], 127 (2) [I+]. 122 (3) [C7H3OF+], 94 (17) [C6H3F+]; HRMS (EI) calculated value C7H4O2FI [M+] 265.9240, measured value 249.9258.
References
[1] Tetrahedron Letters, 2013, vol. 54, # 40, p. 5445 - 5447
4-FLUORO-2-IODOBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
4-FLUORO-2-IODOBENZOIC ACID Suppliers
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View Lastest Price from 4-FLUORO-2-IODOBENZOIC ACID manufacturers
- Product
- 4-FLUORO-2-IODOBENZOIC ACID 56096-89-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- 4-FLUORO-2-IODOBENZOIC ACID 56096-89-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 4-FLUORO-2-IODOBENZOIC ACID 56096-89-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09