4-HYDROXY-2-METHYLBENZOIC ACID 98

Product Name: 4-HYDROXY-2-METHYLBENZOIC ACID 98
CAS No.: 578-39-2
Chemical Name: 4-HYDROXY-2-METHYLBENZOIC ACID 98
Synonyms: 4-HYDROXY-2-METHYLBE;4-hydroxy-o-toluic acid;2-Methyl-4-hydroxybenzoic acid;4-Hydroxy-2-methylbenzoicAcid>Benzoic acid, 4-hydroxy-2-Methyl-;4-HYDROXY-2-METHYLBENZOIC ACID 98;4-Hydroxy-2-Methylbenzoic acid 98%;4-Hydroxy-o-toluic acid, 4-Carboxy-m-cresol;4-Hydroxy-2-Methyl benzoic acid/4-hydroxy-o-toluic acid
CBNumber: CB0498892
Molecular Formula: C8H8O3
Formula Weight: 152.15
MOL File: 578-39-2.mol

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4-HYDROXY-2-METHYLBENZOIC ACID 98 Property

Melting point:: 177-181 °C
Boiling point:: 339.1±30.0 °C(Predicted)
Density: 1.304±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.46±0.25(Predicted)
color: White to Light yellow to Light orange
InChI: InChI=1S/C8H8O3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3,(H,10,11)
InChIKey: BBMFSGOFUHEVNP-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=C(O)C=C1C
CAS DataBase Reference: 578-39-2

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 2
HS Code: 29182900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 653160
Product name: 4-Hydroxy-2-methylbenzoic acid
Purity: 98%
Packaging: 10g
Price: $155
Updated: 2025/07/31

Sigma-Aldrich

Product number: 653160
Product name: 4-Hydroxy-2-methylbenzoic acid
Purity: 98%
Packaging: 1g
Price: $63
Updated: 2023/06/20

TCI Chemical

Product number: H1311
Product name: 4-Hydroxy-2-methylbenzoic Acid
Purity: >98.0%(GC)
Packaging: 5g
Price: $53
Updated: 2025/07/31

TCI Chemical

Product number: H1311
Product name: 4-Hydroxy-2-methylbenzoic Acid
Purity: >98.0%(GC)
Packaging: 25g
Price: $166
Updated: 2025/07/31

TRC

Product number: H972645
Product name: 4-Hydroxy-2-methylbenzoic acid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

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4-HYDROXY-2-METHYLBENZOIC ACID 98 Chemical Properties,Usage,Production

Chemical Properties

White or pink crystalline powder

Definition

ChEBI: 4-hydroxy-2-methylbenzoic acid is a hydroxybenzoic acid.

Synthesis

6245-57-4

578-39-2

General procedure for the synthesis of 4-hydroxy-2-methylbenzoic acid from 4-methoxy-2-methylbenzoic acid: boron tribromide (20 mmol, 5 g, 10 eq.) was slowly added to a solution of 4-methoxy-2-methylbenzoic acid (2 mmol, 0.332 g) in dichloromethane (20 mL) under argon protection. The reaction mixture was stirred at room temperature until high performance liquid chromatography (HPLC) analysis showed complete consumption of the feedstock. Subsequently, 0.1 M hydrochloric acid (20 mL) was added to the reaction system to quench the reaction and the insoluble material was removed by filtration. The aqueous phase was concentrated under reduced pressure and the residue was dissolved in methanol and concentrated again under reduced pressure to remove the solvent. This dissolution-concentration process was repeated three times, resulting in purified 4-hydroxy-2-methylbenzoic acid as a yellow solid (0.24 g, 80% yield).

References

[1] European Journal of Organic Chemistry, 2008, # 5, p. 816 - 825
[2] Patent: WO2006/64286, 2006, A1. Location in patent: Page/Page column 93-94
[3] Patent: WO2007/144379, 2007, A1. Location in patent: Page/Page column 39
[4] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987, vol. 26, p. 679 - 682
[5] Patent: WO2006/79099, 2006, A2. Location in patent: Page/Page column 68; 69

4-HYDROXY-2-METHYLBENZOIC ACID 98 Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY-2-METHYLBENZOIC ACID 98 Suppliers

Americas 1 China 170 Europe 1 India 13 Japan 1 Switzerland 1 United Kingdom 2 United States 19 Global 208

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View Lastest Price from 4-HYDROXY-2-METHYLBENZOIC ACID 98 manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 4-HYDROXY-2-METHYLBENZOIC ACID 578-39-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-09-08

Shaanxi Dideu New Materials Co. Ltd

Product: 4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-12

Changzhou waston chemical technology Co.,Ltd

Product: 4-HYDROXY-2-METHYLBENZOIC ACID 98 578-39-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: follow your request
Release date: 2023-06-01

578-39-2, 4-HYDROXY-2-METHYLBENZOIC ACID 98Related Search:

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4-Hydroxy-2-Methylbenzoic acid 98%

4-HYDROXY-2-METHYLBENZOIC ACID 98

4-hydroxy-o-toluic acid

2-Methyl-4-hydroxybenzoic acid

4-HYDROXY-2-METHYLBE

Benzoic acid, 4-hydroxy-2-Methyl-

4-Hydroxy-o-toluic acid, 4-Carboxy-m-cresol

4-Hydroxy-2-methylbenzoicAcid&gt

4-Hydroxy-2-Methyl benzoic acid/4-hydroxy-o-toluic acid

578-39-2

C8

Carbonyl Compounds

Carboxylic Acids