3-(Trifluoromethyl)benzylamine
- Product Name
- 3-(Trifluoromethyl)benzylamine
- CAS No.
- 2740-83-2
- Chemical Name
- 3-(Trifluoromethyl)benzylamine
- Synonyms
- [3-(TRIFLUOROMETHYL)PHENYL]METHANAMINE;RARECHEM AL BW 0022;TIMTEC-BB SBB006691;3-(Trifluoromethyl)b;M-TRIFLUOROMETHYL BENZYLAMINE;3-(TRIFLUOROMETHYL)BENZYLAMINE;3-(Trifluoromethyl)benzylamine98%;3-(Trifluoromethyl)benzylamine 98%;3-(Trifluoromethyl)benzylamine, 97+%;3-(Trifluoromethyl)benzenemethanamine
- CBNumber
- CB0665638
- Molecular Formula
- C8H8F3N
- Formula Weight
- 175.15
- MOL File
- 2740-83-2.mol
3-(Trifluoromethyl)benzylamine Property
- Melting point:
- 176.5-178.5 °C
- Boiling point:
- 93-97 °C (22 mmHg)
- Density
- 1.222 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.463(lit.)
- Flash point:
- 160 °F
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- pka
- 8.69±0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.222
- color
- Clear colorless to yellow
- Water Solubility
- insoluble
- Sensitive
- Air Sensitive
- BRN
- 1102465
- InChI
- InChI=1S/C8H8F3N/c9-8(10,11)7-3-1-2-6(4-7)5-12/h1-4H,5,12H2
- InChIKey
- YKNZTUQUXUXTLE-UHFFFAOYSA-N
- SMILES
- C1(CN)=CC=CC(C(F)(F)F)=C1
- CAS DataBase Reference
- 2740-83-2(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 22-34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2735 8/PG 3
- WGK Germany
- 2
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29214980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263494
- Product name
- 3-(Trifluoromethyl)benzylamine
- Purity
- 98%
- Packaging
- 5g
- Price
- $67.6
- Updated
- 2025/07/31
- Product number
- 263494
- Product name
- 3-(Trifluoromethyl)benzylamine
- Purity
- 98%
- Packaging
- 25g
- Price
- $221
- Updated
- 2025/07/31
- Product number
- T896668
- Product name
- 3-(Trifluoromethyl)benzylamine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- T896668
- Product name
- 3-(Trifluoromethyl)benzylamine
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 007603
- Product name
- 3-(Trifluoromethyl)benzylamine
- Purity
- 98%
- Packaging
- 25g
- Price
- $45
- Updated
- 2021/12/16
3-(Trifluoromethyl)benzylamine Chemical Properties,Usage,Production
Chemical Properties
clear colorless to yellowish liquid
Uses
3-(Trifluoromethyl)benzylamine has been used in the preparation of 6-substituted purines.
Synthesis
402-23-3
227616-77-5
2740-83-2
437761-03-0
Synthesis of (6S)-3-{[(benzyloxy)carbonyl][3-(trifluoromethyl)benzyl]amino}-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-A]pyrimidine-6-carboxylic acid from 3-(trifluoromethyl)benzyl bromide and (S)-3-(((benzyloxy)carbonyl)amino)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine -6-carboxylic acid (12a) was performed in the following general steps: to a mixture of acid 1i (4.50 g, 13.7 mmol) in 70 mL THF at 0 °C was added 3-(trifluoromethyl)benzyl bromide (8.35 mL, 54.7 mmol), NaH (60% dispersed in oil, 1.64 g, 41.4 mmol) and TBAI (100 mg, catalytic amount). The reaction mixture was stirred at room temperature for 15 h. The reaction was then quenched by the addition of 50 mL of H2O. The volatile solvent was removed by rotary evaporation and the resulting aqueous solution was partitioned with Et2O. The organic phase was extracted with 20% saturated NaHCO3 solution (3 times). The combined organic extracts were acidified with 1N HCl and extracted with EtOAc (5 times). The combined organic extracts were washed with brine, dried (Na2SO4), and concentrated to give 6.18 g (93% yield) of 3-(trifluoromethyl)benzylamine (12a), a product that could be used in the next step without further purification.
References
[1] Patent: US2003/64962, 2003, A1
3-(Trifluoromethyl)benzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(Trifluoromethyl)benzylamine manufacturers
- Product
- 3-(Trifluoromethyl)benzylamine 2740-83-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- 3-(Trifluoromethyl)benzylamine 2740-83-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 3-(Trifluoromethyl)benzylamine 2740-83-2
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09