5-BROMOCYTIDINE

Product Name: 5-BROMOCYTIDINE
CAS No.: 3066-86-2
Chemical Name: 5-BROMOCYTIDINE
Synonyms: 5-Br-Cr;5-Br-Cytidine;5-BROMOCYTIDINE;Cytidine, 5-bromo-;5-Bromo-D-cytidine;5-BROMOCYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM;4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one;4-Amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
CBNumber: CB0724052
Molecular Formula: C9H12BrN3O5
Formula Weight: 322.11
MOL File: 3066-86-2.mol

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5-BROMOCYTIDINE Property

Melting point:: 183-185 °C
Boiling point:: 555.4±60.0 °C(Predicted)
Density: 2.28±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 13.48±0.70(Predicted)
form: Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4165
Product name: 5-Bromocytidine
Packaging: 500MG
Price: $330
Updated: 2025/07/31

TRC

Product number: B701358
Product name: 5-Bromocytidine
Packaging: 500mg
Price: $110
Updated: 2021/12/16

Usbiological

Product number: 295426
Product name: 5-Bromocytidine
Packaging: 500mg
Price: $360
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NB06281
Product name: 5-Bromocytidine
Packaging: 500mg
Price: $80
Updated: 2021/12/16

Matrix Scientific

Product number: 098565
Product name: 5-Bromocytidine
Purity: 95+%
Packaging: 1g
Price: $95
Updated: 2021/12/16

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5-BROMOCYTIDINE Chemical Properties,Usage,Production

Description

5-Bromocytidine is a pyrimidine nucleoside. 5-Bromocytidine is used in the synthesis of substituted cytidine analogs identification of potent inhibitor of viral rnadependent RNA polymerases and has been shown to inhibit the replication of influenza virus in cell culture.

Uses

5-Bromocytidine is a useful research chemical used in the preparation and synthesis of substituted cytidine analogs identification of potent inhibitor of viral rnadependent RNA polymerases.

Synthesis

65-46-3

3066-86-2

The general procedure for the synthesis of 4-amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one from cytidine was as follows: using a typical method of bromination of unprotected nucleosides, 1,3-dibromo-5,5-dimethylglycolactonium (DBH, 323 mg, 1.13 mmol ) was added to a stirred solution of cytidine (1d, 500 mg, 2.05 mmol) in N,N-dimethylformamide (DMF, 5 mL). The reaction mixture was stirred at room temperature for 20 min or monitored by thin layer chromatography (TLC) until the starting material completely disappeared and a less polar product was formed. Subsequently, the volatile solvent was evaporated under reduced pressure and the residue was co-evaporated with acetonitrile (MeCN) to remove the residual DMF.The resulting light-colored solid was recrystallized from hot acetone to give the target product 2d (500 mg, 75% yield) as colorless crystals with physicochemical properties consistent with those reported in the literature.

References

[1] Organic and Biomolecular Chemistry, 2014, vol. 12, # 30, p. 5634 - 5644
[2] Synthesis, 2009, # 23, p. 3957 - 3962
[3] Tetrahedron Letters, 2012, vol. 53, # 26, p. 3333 - 3336
[4] Molecules, 2013, vol. 18, # 10, p. 12740 - 12750
[5] Journal of the American Chemical Society, 1995, vol. 117, # 2, p. 704 - 714

5-BROMOCYTIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMOCYTIDINE Suppliers

China 64 India 1 Russia 1 Switzerland 3 United Kingdom 4 United States 9 Global 82

Carbosynth

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Country: United Kingdom
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Carbosynth Limited

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CARBONE SCIENTIFIC CO.,LTD

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Glentham Life Sciences

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View Lastest Price from 5-BROMOCYTIDINE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Bromocytidine 3066-86-2
Price: US $0.00-0.00/KG
Min. Order: 100g
Purity: 98%min
Supply Ability: 100kgs
Release date: 2021-09-07

Career Henan Chemical Co

Product: 5-BROMOCYTIDINE 3066-86-2
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-08-02

3066-86-2, 5-BROMOCYTIDINERelated Search:

5-IODOURIDINE 2'-O-Methyluridine 7-DEAZA-7-IODO-2'-DEOXYADENOSINE 5-Iodocytidine 5,2'-O-Dimethyluridine 7-DEAZA-2'-DEOXYGUANOSINE 7-DEAZA-2'-DEOXYADENOSINE 7-DEAZA-7-IODO-2'-DEOXYGUANOSINE 5-Bromouridine 2'-DEOXY-5-BROMOCYTIDINE 5-Bromo-2-hydroxypyrimidine 6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE 5-BROMOCYTIDINE 6-BROMOCYTIDINE 2'-Deoxy-2'-methylene-5-bromocytidine 3'-Deoxy-5-bromocytidine 5-BROMOCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT

5-BROMOCYTIDINE

5-Bromo-D-cytidine

5-BROMOCYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM

4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

5-Br-Cytidine

Cytidine, 5-bromo-

5-Br-Cr

4-Amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one

3066-86-2

C9H12BrN3O5